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LOC129660479 ReSE screen-validated silencer GRCh37_chr1:211306707-211306897 [ Homo sapiens (human) ]

Gene ID: 129660479, updated on 12-Sep-2024

Summary

Gene symbol
LOC129660479
Gene description
ReSE screen-validated silencer GRCh37_chr1:211306707-211306897
Gene type
biological region
Feature type(s)
regulatory: silencer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region used in a lentiviral ReSE (repressive ability of silencer elements) screen that assays for cell survival based on transcriptional repression of an apoptosis-inducing fusion protein. This region was identified as a functional silencer in phorbol 12-myristate 13-acetate-treated (for megakaryocytic differentiation) K562 erythroleukemia cells. [provided by RefSeq, Apr 2023]
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Genomic context

See LOC129660479 in Genome Data Viewer
Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (211133365..211133555)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (210379045..210379235)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (211306707..211306897)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372901 Neighboring gene MPRA-validated peak678 silencer Neighboring gene potassium voltage-gated channel subfamily H member 1 Neighboring gene MPRA-validated peak679 silencer Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_3130 Neighboring gene MPRA-validated peak680 silencer Neighboring gene importin 8 pseudogene 1 Neighboring gene Sharpr-MPRA regulatory region 3630 Neighboring gene MPRA-validated peak681 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1781 Neighboring gene KCNH1 intronic transcript 1 Neighboring gene ribosomal protein S25 pseudogene 2 Neighboring gene PRELID1 pseudogene 5

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_157516.1 

    Range
    101..291
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    211133365..211133555
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    210379045..210379235
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)