U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG43324 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 12798331, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
CG43324provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0263029
Locus tag
Dmel_CG43324
See related
AllianceGenome:FB:FBgn0263029
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG15844; Dmel\CG43324
Old locus tag
Dmel_CG15844
Summary
Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Orthologous to several human genes including GNG2 (G protein subunit gamma 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CG43324 in Genome Data Viewer
Location:
54C8-54C8; 2-83 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17563606..17564351)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13451111..13451856)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Misexpression suppressor of ras 4 Neighboring gene Kinesin-like protein at 54D Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Nucleostemin 2 Neighboring gene Plenty of SH3s Neighboring gene Ubiquinol-cytochrome c reductase 6.4 kDa subunit

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The Drosophila actin nucleator DAAM is essential for left-right asymmetry. Chougule A, et al. PLoS Genet, 2020 Apr. PMID 32324733, Free PMC Article
  2. The pleiotropic functions of Pri smORF peptides synchronize leg development regulators. Markus D, et al. PLoS Genet, 2023 Oct. PMID 37903161, Free PMC Article
  3. The molecular landscape of neural differentiation in the developing Drosophila brain revealed by targeted scRNA-seq and multi-informatic analysis. Michki NS, et al. Cell Rep, 2021 Apr 27. PMID 33909998, Free PMC Article
  4. A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Guichard A, et al. Cell Rep, 2023 Aug 29. PMID 37480566, Free PMC Article
  5. Ultra-deep sequencing of ribosome-associated poly-adenylated RNA in early Drosophila embryos reveals hundreds of conserved translated sORFs. Li H, et al. DNA Res, 2016 Dec. PMID 27559081, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables G-protein beta-subunit binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
part_of heterotrimeric G-protein complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
CG43324-PA

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    17563606..17564351
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001259470.2 → NP_001246399.1  uncharacterized protein Dmel_CG43324 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246399.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K838
    Conserved Domains (1) summary
    cd00068
    Location:5 → 61
    GGL; G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4K838 A0A0B4K838

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.