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mir-279 mir-279 stem loop [ Drosophila melanogaster (fruit fly) ]

Gene ID: 12798294, updated on 9-Dec-2024

Summary

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Official Symbol
mir-279provided by FlyBase
Official Full Name
mir-279 stem loopprovided by FlyBase
Primary source
FLYBASE:FBgn0262448
Locus tag
Dmel_CR43015
See related
miRBase:MI0000363; AllianceGenome:FB:FBgn0262448
Gene type
ncRNA
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
0962/07; 279; CR33590; CR43015; dme-mir-279; dme-miR-279; dme-miR-279-3p; Dmel\CR43015; l(3)S096207; miR; miR-279; Mir-279; MiR-279; MIR-279; miR-279-3p; mir-279a; mir279; miR279; miRNA-279
Old locus tag
Dmel_CR33590
Summary
Enables mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Involved in several processes, including locomotor rhythm; negative regulation of cell differentiation; and regulation of signal transduction. Is expressed in several structures, including adult brain; anterior spiracle primordium; embryonic head sensory system; external sensory organ precursor cell; and larval foregut atrium. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See mir-279 in Genome Data Viewer
Location:
99A1-99A1; 3-98 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29215585..29215684)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25041307..25041406)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Metazoan SpoT homolog-1 Neighboring gene Cytochrome c1-like Neighboring gene long non-coding RNA::CR31044 Neighboring gene mir-996 stem loop Neighboring gene eukaryotic translation elongation factor 1 gamma

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Adaptation of molecular circadian clockwork to environmental changes: a role for alternative splicing and miRNAs. Bartok O, et al. Proc Biol Sci, 2013 Aug 22. PMID 23825200, Free PMC Article
  2. Enhanced Northern Blot detection of small RNA species in Drosophila melanogaster. Laneve P, et al. J Vis Exp, 2014 Aug 21. PMID 25177861, Free PMC Article
  3. Microguards and micromessengers of the genome. Green D, et al. Heredity (Edinb), 2016 Feb. PMID 26419338, Free PMC Article
  4. MicroRNAs influence reproductive responses by females to male sex peptide in Drosophila melanogaster. Fricke C, et al. Genetics, 2014 Dec. PMID 25245794, Free PMC Article
  5. miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay. Djuranovic S, et al. Science, 2012 Apr 13. PMID 22499947, Free PMC Article

See all (121) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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  • alternate names: miR-279; lethal (3) S096207
  • mir-279-RA; Dmel\mir-279-RA; CR43015-RA; Dmel\CR43015-RA
  • mir-279-RB; Dmel\mir-279-RB; CR43015-RB; Dmel\CR43015-RB
  • mir-279-RM; Dmel\mir-279-RM; CR43015-RM; Dmel\CR43015-RM

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables mRNA 3'-UTR binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables mRNA base-pairing translational repressor activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in brain morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in locomotion involved in locomotory behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in locomotor rhythm IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in miRNA-mediated gene silencing by mRNA destabilization IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in miRNA-mediated post-transcriptional gene silencing IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in miRNA-mediated post-transcriptional gene silencing IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of epidermal growth factor receptor signaling pathway IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in negative regulation of neuroblast proliferation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of receptor signaling pathway via JAK-STAT IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of receptor signaling pathway via JAK-STAT IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of Notch signaling pathway IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in positive regulation of Notch signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of locomotor rhythm IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in startle response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in wing disc dorsal/ventral pattern formation IGI
Inferred from Genetic Interaction
more info
 PubMed 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    29215585..29215684
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. NR_048508.1 RNA Sequence

    Status: REVIEWED

Gene LinkOut

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Molecular Biology Databases
Research Materials