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LOC127896053 OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:37006222-37006886 [ Homo sapiens (human) ]

Gene ID: 127896053, updated on 12-Sep-2024

Summary

Gene symbol
LOC127896053
Gene description
OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:37006222-37006886
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors and is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

See LOC127896053 in Genome Data Viewer
Location:
chromosome: 22
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (36610175..36610839)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (37070374..37071038)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (37006222..37006886)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18936 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18937 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18938 Neighboring gene HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 pseudogene Neighboring gene eukaryotic translation initiation factor 3 subunit D Neighboring gene Sharpr-MPRA regulatory region 13009 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:36959107-36959622 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:36966399-36966990 Neighboring gene calcium voltage-gated channel auxiliary subunit gamma 2 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:37004893-37005557 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:37005558-37006221 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:37080862-37081403 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:37104667-37104810 Neighboring gene CACNG2 divergent transcript Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:37121981-37122481 Neighboring gene uncharacterized LOC124905112 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr22:37161913-37163112 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13671 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr22:37171863-37172426 Neighboring gene intraflagellar transport 27

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_145605.1 

    Range
    101..765
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    36610175..36610839
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    37070374..37071038
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)