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LOC127894905 H3K4me1 hESC enhancer GRCh37_chr21:45401849-45402610 [ Homo sapiens (human) ]

Gene ID: 127894905, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127894905
Gene description
H3K4me1 hESC enhancer GRCh37_chr21:45401849-45402610
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127894905 in Genome Data Viewer
Location:
chromosome: 21
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (43981968..43982729)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (42337589..42338350)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (45401849..45402610)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45339493-45340392 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45340393-45341290 Neighboring gene Sharpr-MPRA regulatory region 2423 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:45342191-45343088 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:45344887-45345786 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:45345787-45346684 Neighboring gene RNA, U6 small nuclear 859, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45351938-45352438 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45354036-45354854 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18558 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45358304-45359204 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45359205-45360103 Neighboring gene ReSE screen-validated silencer GRCh37_chr21:45360643-45360814 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45363715-45364558 Neighboring gene uncharacterized LOC105372826 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45376043-45376543 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45401087-45401848 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:45402611-45403372 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13375 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45405825-45406355 Neighboring gene uncharacterized LOC105372829 Neighboring gene RNA, U6 small nuclear 1150, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13376 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13377 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18560 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18561 Neighboring gene trafficking protein particle complex subunit 10 Neighboring gene ReSE screen-validated silencer GRCh37_chr21:45452244-45452456 Neighboring gene H2A.Z histone pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_144539.1 

    Range
    101..862
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

    Range
    43981968..43982729
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060945.1 Alternate T2T-CHM13v2.0

    Range
    42337589..42338350
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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