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LOC127891074 NANOG hESC enhancer GRCh37_chr19:27877672-27878173 [ Homo sapiens (human) ]

Gene ID: 127891074, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127891074
Gene description
NANOG hESC enhancer GRCh37_chr19:27877672-27878173
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127891074 in Genome Data Viewer
Location:
chromosome: 19
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (27386764..27387265)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (29907074..29907575)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (27877672..27878173)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904678 Neighboring gene hepatitis A virus cellular receptor 1 pseudogene 1 Neighboring gene NANOG hESC enhancer GRCh37_chr19:24584392-24584893 Neighboring gene NANOG hESC enhancer GRCh37_chr19:24585417-24585918 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:24625458-24626443 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:24630995-24631601 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27732451-27733302 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27733303-27734155 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27734156-27735007 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:27735098-27735622 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27739713-27740586 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27738839-27739712 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27737965-27738838 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27736489-27737057 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27735920-27736488 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27737089-27737964 Neighboring gene NANOG hESC enhancer GRCh37_chr19:27808230-27808731 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:27812477-27813220 Neighboring gene NANOG hESC enhancer GRCh37_chr19:27813523-27814024 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:27814077-27814586 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:27836954-27837540 Neighboring gene NANOG hESC enhancer GRCh37_chr19:27844808-27845309 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:27874272-27875240 Neighboring gene NANOG hESC enhancer GRCh37_chr19:27875298-27875799 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:27894379-27895360 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:27897397-27897916 Neighboring gene uncharacterized LOC105372345 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14401 Neighboring gene long intergenic non-protein coding RNA 662 Neighboring gene long intergenic non-protein coding RNA 2987

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_140965.1 

    Range
    101..602
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    27386764..27387265
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    29907074..29907575
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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