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LOC127890263 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:6586479-6587231 [ Homo sapiens (human) ]

Gene ID: 127890263, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127890263
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:6586479-6587231
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127890263 in Genome Data Viewer
Location:
chromosome: 19
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (6586468..6587220)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (6576122..6576875)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (6586479..6587231)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13841 Neighboring gene TGFBR1 pseudogene 1 Neighboring gene MPRA-validated peak3304 silencer Neighboring gene chloride intracellular channel 4 pseudogene 2 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:6577143-6577827 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:6579197-6579879 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:6585724-6586478 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13844 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13845 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13846 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13847 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13848 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13849 Neighboring gene CD70 molecule Neighboring gene ribosomal protein L7 pseudogene 50 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13850 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13851 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13852 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:6631163-6631664 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13853 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13854 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13855 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13856 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13857 Neighboring gene TNF superfamily member 14

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_140209.1 

    Range
    101..853
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    6586468..6587220
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    6576122..6576875
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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