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LOC127888925 OCT4-NANOG hESC enhancer GRCh37_chr18:19490742-19491339 [ Homo sapiens (human) ]

Gene ID: 127888925, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127888925
Gene description
OCT4-NANOG hESC enhancer GRCh37_chr18:19490742-19491339
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127888925 in Genome Data Viewer
Location:
chromosome: 18
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (21910781..21911378)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (22095819..22096416)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (19490742..19491339)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene MIB E3 ubiquitin protein ligase 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr18:19442056-19442255 Neighboring gene ribosomal protein L34 pseudogene 32 Neighboring gene RNA, U6 small nuclear 1038, pseudogene Neighboring gene uncharacterized LOC105372016 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr18:19513802-19514448 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr18:19514449-19515095 Neighboring gene RNA, 5S ribosomal pseudogene 451 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:19571122-19571994 Neighboring gene long intergenic non-protein coding RNA 1900

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_138485.1 

    Range
    101..698
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

    Range
    21910781..21911378
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060942.1 Alternate T2T-CHM13v2.0

    Range
    22095819..22096416
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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