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LOC127888494 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:79699122-79699658 [ Homo sapiens (human) ]

Gene ID: 127888494, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127888494
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:79699122-79699658
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127888494 in Genome Data Viewer
Location:
chromosome: 17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (81732092..81732628)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (82649024..82649560)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (79699122..79699658)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:79669881-79670484 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9147 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:79677211-79677911 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12978 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9148 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9149 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9150 Neighboring gene mitochondrial ribosomal protein L12 Neighboring gene solute carrier family 25 member 10 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:79689497-79690038 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:79697182-79697401 Neighboring gene uncharacterized LOC105371929 Neighboring gene uncharacterized LOC105376789 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:79761495-79761994 Neighboring gene glucagon receptor Neighboring gene Sharpr-MPRA regulatory region 4607 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:79781934-79782157 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:79783828-79784461 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:79789117-79789630 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:79789631-79790144 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:79791171-79791684 Neighboring gene MAPK regulated corepressor interacting protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_138089.1 

    Range
    101..637
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    81732092..81732628
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    82649024..82649560
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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