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LOC127886151 NANOG-H3K27ac hESC enhancer GRCh37_chr17:19363487-19364033 [ Homo sapiens (human) ]

Gene ID: 127886151, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127886151
Gene description
NANOG-H3K27ac hESC enhancer GRCh37_chr17:19363487-19364033
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor and is marked by the H3K27ac histone modification. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127886151 in Genome Data Viewer
Location:
chromosome: 17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (19460174..19460720)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (19408299..19408845)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (19363487..19364033)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 2094 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr17:19336510-19337048 Neighboring gene uncharacterized LOC105371574 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:19344229-19345013 Neighboring gene ribosomal protein S2 pseudogene 46 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:19356211-19356712 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:19356713-19357212 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:19361301-19361846 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:19361847-19362393 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr17:19362394-19362939 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:19364034-19364580 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:19366221-19366766 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:19374315-19374824 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:19378419-19379256 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:19384743-19385658 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr17:19385659-19386572 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:19395941-19396458 Neighboring gene ribosomal protein L17 pseudogene 43 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr17:19408793-19409392 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8293 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8294 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8295 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8296 Neighboring gene tRNA-Trp (anticodon CCA) 2-1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_135880.1 

    Range
    101..647
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    19460174..19460720
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    19408299..19408845
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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