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LOC127883481 H3K27ac hESC enhancer GRCh37_chr16:24354853-24355354 [ Homo sapiens (human) ]

Gene ID: 127883481, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127883481
Gene description
H3K27ac hESC enhancer GRCh37_chr16:24354853-24355354
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127883481 in Genome Data Viewer
Location:
chromosome: 16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (24343532..24344033)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (24620385..24620886)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (24354853..24355354)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene MED14-independent group 3 enhancer GRCh37_chr16:24257631-24258830 Neighboring gene long intergenic non-protein coding RNA 2194 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:24267404-24268131 Neighboring gene calcium voltage-gated channel auxiliary subunit gamma 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:24327354-24327854 Neighboring gene small nucleolar RNA SNORA1 Neighboring gene NANOG hESC enhancer GRCh37_chr16:24368887-24369391 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr16:24392929-24394128 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr16:24394102-24394791 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10599 Neighboring gene RNA, U7 small nuclear 24 pseudogene Neighboring gene uncharacterized LOC105371143 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr16:24493839-24494713

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_133441.1 

    Range
    101..602
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    24343532..24344033
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    24620385..24620886
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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