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LOC127829116 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:29454119-29454628 [ Homo sapiens (human) ]

Gene ID: 127829116, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127829116
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:29454119-29454628
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127829116 in Genome Data Viewer
Location:
chromosome: 15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (29161916..29162425)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (26940298..26940807)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (29454119..29454628)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:29105715-29106316 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:29120363-29120984 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:29120985-29121605 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:29121606-29122226 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29122227-29122847 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr15:29141496-29142056 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:29144665-29144856 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29146721-29147272 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29147273-29147824 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29145615-29146168 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29148359-29148860 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29148861-29149360 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:29210321-29210843 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29211011-29211600 Neighboring gene ferritin light chain pseudogene 11 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29227603-29228102 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29240656-29241156 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29246587-29247088 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29247089-29247588 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29247601-29248114 Neighboring gene amyloid beta precursor protein binding family A member 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29283117-29283618 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29283619-29284118 Neighboring gene MPRA-validated peak2281 silencer Neighboring gene ReSE screen-validated silencer GRCh37_chr15:29307813-29308019 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29356146-29356657 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29356658-29357170 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29379537-29380038 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:29407365-29408165 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:29424556-29425172 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29432077-29432890 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:29454629-29455137 Neighboring gene endosomal transmembrane epsin interactor 2 Neighboring gene DDB1 and CUL4 associated factor 6 pseudogene Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:29561321-29561822 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:29561823-29562322 Neighboring gene NSE3 homolog, SMC5-SMC6 complex component

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_130598.1 

    Range
    101..610
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    29161916..29162425
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_011332701.1 Reference GRCh38.p14 PATCHES

    Range
    1324995..1325504
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

  1. NT_187660.1 Reference GRCh38.p14 ALT_REF_LOCI_2

    Range
    1437479..1437988
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    26940298..26940807
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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