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LOC127820513 H3K4me1 hESC enhancer GRCh37_chr11:15096041-15096542 [ Homo sapiens (human) ]

Gene ID: 127820513, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127820513
Gene description
H3K4me1 hESC enhancer GRCh37_chr11:15096041-15096542
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127820513 in Genome Data Viewer
Location:
chromosome: 11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (15074495..15074996)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (15170858..15171359)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (15096041..15096542)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:14993078-14993724 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3175 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr11:14996341-14996870 Neighboring gene Sharpr-MPRA regulatory region 7615 Neighboring gene olfactory receptor family 7 subfamily E member 41 pseudogene Neighboring gene calcitonin related polypeptide alpha Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3176 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3177 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4478 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:15135643-15136176 Neighboring gene calcitonin related polypeptide beta Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:15196965-15197488 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:15197489-15198010 Neighboring gene INSC spindle orientation adaptor protein Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3178 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:15260043-15260544 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:15260545-15261044 Neighboring gene NANOG hESC enhancer GRCh37_chr11:15363023-15363618 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:15454895-15455061 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:15467942-15469141 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:15581971-15582472 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:15583102-15584301 Neighboring gene VISTA enhancer hs692 Neighboring gene uncharacterized LOC105376568 Neighboring gene long intergenic non-protein coding RNA 2751 Neighboring gene MPRA-validated peak1210 silencer Neighboring gene NANOG hESC enhancer GRCh37_chr11:15610492-15610993 Neighboring gene NANOG hESC enhancer GRCh37_chr11:15643853-15644482

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_121972.1 

    Range
    101..602
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    15074495..15074996
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    15170858..15171359
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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