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LOC127814421 OCT4-NANOG hESC enhancer GRCh37_chr9:13251447-13252059 [ Homo sapiens (human) ]

Gene ID: 127814421, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127814421
Gene description
OCT4-NANOG hESC enhancer GRCh37_chr9:13251447-13252059
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127814421 in Genome Data Viewer
Location:
chromosome: 9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (13251448..13252060)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (13260845..13261457)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (13251447..13252059)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA, C/D box 137 Neighboring gene peroxiredoxin 1 pseudogene 1 Neighboring gene lupus La protein-like Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:13037568-13038084 Neighboring gene multiple PDZ domain crumbs cell polarity complex component Neighboring gene Sharpr-MPRA regulatory region 14432 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:13277167-13277882 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:13277883-13278598 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:13278599-13279314 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr9:13369413-13369918 Neighboring gene long intergenic non-protein coding RNA 1235 Neighboring gene uncharacterized LOC105375977

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_115942.1 

    Range
    101..713
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    13251448..13252060
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    13260845..13261457
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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