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LOC127458479 H3K4me1 hESC enhancer GRCh37_chr8:2005611-2006111 [ Homo sapiens (human) ]

Gene ID: 127458479, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127458479
Gene description
H3K4me1 hESC enhancer GRCh37_chr8:2005611-2006111
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127458479 in Genome Data Viewer
Location:
chromosome: 8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (2057493..2057993)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (1836013..1836513)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (2005611..2006111)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene KBTBD11 overlapping transcript 1 Neighboring gene KBTBD11 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1926153-1926712 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1926713-1927271 Neighboring gene kelch repeat and BTB domain containing 11 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:1969593-1970582 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:1978746-1978950 Neighboring gene VISTA enhancer hs2514 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:2008946-2009868 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:2009869-2010789 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr8:2012487-2013034 Neighboring gene myomesin 2 Neighboring gene microRNA 7160 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr8:2049318-2050517 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr8:2053383-2054582 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:2084289-2084796 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:2085784-2086284 Neighboring gene uncharacterized LOC105377781 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:2128908-2129408 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:2130059-2130239

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_113252.1 

    Range
    101..601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    2057493..2057993
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187576.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    240821..241321
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    1836013..1836513
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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