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LOC127405601 NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:27100475-27100988 [ Homo sapiens (human) ]

Gene ID: 127405601, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127405601
Gene description
NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:27100475-27100988
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor and is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127405601 in Genome Data Viewer
Location:
chromosome: 6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (27132696..27133209)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (27001511..27002024)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (27100475..27100988)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene tRNA-Ser (anticodon GCT) 1-1 Neighboring gene RNA, U2 small nuclear 62, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24259 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24260 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24261 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24262 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24263 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24264 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24265 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:27100989-27101504 Neighboring gene H2B clustered histone 11 Neighboring gene H2A clustered histone 11 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:27107017-27107609 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:27107610-27108201 Neighboring gene H2B clustered histone 12 Neighboring gene H4 clustered histone 9 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24268 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:27114061-27114977 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24270 Neighboring gene H2A clustered histone 12

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_107572.1 

    Range
    101..614
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    27132696..27133209
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    27001511..27002024
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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