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LOC127403486 OCT4-NANOG hESC enhancer GRCh37_chr5:106808214-106808968 [ Homo sapiens (human) ]

Gene ID: 127403486, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127403486
Gene description
OCT4-NANOG hESC enhancer GRCh37_chr5:106808214-106808968
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127403486 in Genome Data Viewer
Location:
chromosome: 5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (107472513..107473267)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (107975479..107976233)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (106808214..106808968)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 1950 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:106314019-106314772 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:106319287-106320038 Neighboring gene NANOG hESC enhancer GRCh37_chr5:106454169-106454670 Neighboring gene proteasome 26S subunit, ATPase 1 pseudogene 5 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr5:106620899-106622098 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr5:106737319-106737856 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22862 Neighboring gene ephrin A5 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:106801251-106801752 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22863 Neighboring gene NANOG hESC enhancer GRCh37_chr5:106834891-106835392 Neighboring gene Sharpr-MPRA regulatory region 8638 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22864 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16212 Neighboring gene NANOG hESC enhancer GRCh37_chr5:106855351-106855852 Neighboring gene uncharacterized LOC124901038 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr5:106903957-106904492 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:106906417-106907128 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22867 Neighboring gene Sharpr-MPRA regulatory region 13332 Neighboring gene VISTA enhancer hs1734 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr5:106924851-106925777 Neighboring gene Sharpr-MPRA regulatory region 6875 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr5:106946073-106947272 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22869 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16215 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22870 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16214 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16213 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22868 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:107008991-107009490 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16216 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr5:107031758-107032266 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr5:107060476-107061675 Neighboring gene ubiquitin specific peptidase 7 (herpes virus-associated) pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_105435.1 

    Range
    101..855
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    107472513..107473267
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    107975479..107976233
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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