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LOC127274682 H3K4me1 hESC enhancer GRCh37_chr2:127893553-127894054 [ Homo sapiens (human) ]

Gene ID: 127274682, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127274682
Gene description
H3K4me1 hESC enhancer GRCh37_chr2:127893553-127894054
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127274682 in Genome Data Viewer
Location:
chromosome: 2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (127135977..127136478)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (127570881..127571382)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (127893553..127894054)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373604 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:127810732-127811490 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:127811491-127812249 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:127819607-127820223 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:127822028-127823227 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:127824976-127825607 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:127825608-127826238 Neighboring gene bridging integrator 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16481 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16482 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16483 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16484 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16485 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:127844150-127845127 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:127849722-127849889 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:127852973-127853644 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:127853738-127854508 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:127861306-127861858 Neighboring gene Sharpr-MPRA regulatory region 2128 Neighboring gene uncharacterized LOC105373605 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:127894055-127894554 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:127914864-127915364 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:127915365-127915865 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:127922719-127923312 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:127923313-127923906 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:127928522-127929073 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:127940541-127941097 Neighboring gene NIFK pseudogene 9 Neighboring gene Sharpr-MPRA regulatory region 1591 Neighboring gene cytochrome P450 family 27 subfamily C member 1 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr2:127966173-127966722

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_096532.1 

    Range
    101..602
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    127135977..127136478
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    127570881..127571382
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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