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LOC127268068 H3K4me1 hESC enhancer GRCh37_chr1:23118959-23119488 [ Homo sapiens (human) ]

Gene ID: 127268068, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127268068
Gene description
H3K4me1 hESC enhancer GRCh37_chr1:23118959-23119488
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127268068 in Genome Data Viewer
Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (22792466..22792995)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (22617999..22618528)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (23118959..23119488)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:23003627-23004149 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:23004182-23004720 Neighboring gene complement C1q B chain Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:23021074-23021574 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:23021575-23022075 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:23036019-23036304 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 353 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:23043657-23044346 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:23049783-23050297 Neighboring gene EPH receptor B2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:23063222-23063783 Neighboring gene microRNA 4684 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:23066264-23066434 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 354 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 355 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:23082861-23083022 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:23117273-23117773 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:23136274-23136774 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:23136775-23137275 Neighboring gene Sharpr-MPRA regulatory region 697 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:23154258-23154779 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:23163087-23164034 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:23176387-23176888 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:23176889-23177388 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:23179771-23180334 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:23180335-23180896 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 403 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:23191518-23191863 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:23203195-23203794 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:23206043-23206947 Neighboring gene microRNA 4253 Neighboring gene uncharacterized LOC124903874 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:23216005-23216210

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_089929.1 

    Range
    101..630
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    22792466..22792995
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    22617999..22618528
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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