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CNTN1 contactin 1 [ Homo sapiens (human) ]

Gene ID: 1272, updated on 27-Nov-2024

Summary

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Official Symbol
CNTN1provided by HGNC
Official Full Name
contactin 1provided by HGNC
Primary source
HGNC:HGNC:2171
See related
Ensembl:ENSG00000018236 MIM:600016; AllianceGenome:HGNC:2171
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
F3; GP135; MYPCN; CMYO12; CMYP12
Summary
The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Expression
Biased expression in brain (RPKM 51.8), ovary (RPKM 13.6) and 10 other tissues See more
Orthologs
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Genomic context

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See CNTN1 in Genome Data Viewer
Location:
12q12
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (40692439..41072415)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (40652132..41031590)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (41086241..41466217)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene microtubule associated protein 6 pseudogene Neighboring gene MPRA-validated peak1679 silencer Neighboring gene mucin 19, oligomeric (gene/pseudogene) Neighboring gene NANOG hESC enhancer GRCh37_chr12:40912063-40912564 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr12:40959271-40960470 Neighboring gene RNA, U6 small nuclear 713, pseudogene Neighboring gene methionyl aminopeptidase 1 pseudogene Neighboring gene uncharacterized LOC124903069 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr12:41673681-41674880 Neighboring gene PDZ domain containing ring finger 4 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr12:41686587-41687786 Neighboring gene uncharacterized LOC107984499

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Diversity of contactin mRNA in human brain tumors. Rome C, et al. Mol Carcinog, 2006 Oct. PMID 16865674
  2. Overexpression of Contactin 1 promotes growth, migration and invasion in Hs578T breast cancer cells. Chen N, et al. BMC Cell Biol, 2018 Apr 19. PMID 29673312, Free PMC Article
  3. CNTN-1 Enhances Chemoresistance in Human Lung Adenocarcinoma Through Induction of Epithelial-Mesenchymal Transition by Targeting the PI3K/Akt Pathway. Zhang R, et al. Cell Physiol Biochem, 2017. PMID 28934754
  4. Regulated expression of the cell adhesion glycoprotein F3 in adult hypothalamic magnocellular neurons. Pierre K, et al. J Neurosci, 1998 Jul 15. PMID 9651216, Free PMC Article
  5. Upregulated CNTN1 is associated with lymph node metastasis and poor prognosis of colorectal cancer. Li G, et al. Cancer Biomark, 2021. PMID 33104020

See all (91) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Key Molecules in Bladder Cancer Affect Patient Prognosis and Immunotherapy Efficacy: Further Exploration for CNTN1 and EMP1.
    Title: Key Molecules in Bladder Cancer Affect Patient Prognosis and Immunotherapy Efficacy: Further Exploration for CNTN1 and EMP1.
  2. Contactin-1 links autoimmune neuropathy and membranous glomerulonephritis.
    Title: Contactin-1 links autoimmune neuropathy and membranous glomerulonephritis.
  3. The molecular mechanism of gamma-aminobutyric acid against AD: the role of CEBPalpha/circAPLP2/miR-671-5p in regulating CNTN1/2 expression.
    Title: The molecular mechanism of γ-aminobutyric acid against AD: the role of CEBPα/circAPLP2/miR-671-5p in regulating CNTN1/2 expression.
  4. Neuroaxonal and Glial Markers in Patients of the Same Age With Multiple Sclerosis.
    Title: Neuroaxonal and Glial Markers in Patients of the Same Age With Multiple Sclerosis.
  5. Neurofilament-light and contactin-1 association with long-term brain atrophy in natalizumab-treated relapsing-remitting multiple sclerosis.
    Title: Neurofilament-light and contactin-1 association with long-term brain atrophy in natalizumab-treated relapsing-remitting multiple sclerosis.
  6. MicroRNA-200c-targeted contactin 1 facilitates the replication of influenza A virus by accelerating the degradation of MAVS.
    Title: MicroRNA-200c-targeted contactin 1 facilitates the replication of influenza A virus by accelerating the degradation of MAVS.
  7. Serum Contactin-1 in CIDP: A Cross-Sectional Study.
    Title: Serum Contactin-1 in CIDP: A Cross-Sectional Study.
  8. Characteristics of Anti-Contactin1 Antibody-Associated Autoimmune Nodopathies With Concomitant Membranous Nephropathy.
    Title: Characteristics of Anti-Contactin1 Antibody-Associated Autoimmune Nodopathies With Concomitant Membranous Nephropathy.
  9. Contactin-1 is a novel target antigen in membranous nephropathy associated with chronic inflammatory demyelinating polyneuropathy.
    Title: Contactin-1 is a novel target antigen in membranous nephropathy associated with chronic inflammatory demyelinating polyneuropathy.
  10. Upregulated CNTN1 is associated with lymph node metastasis and poor prognosis of colorectal cancer.
    Title: Upregulated CNTN1 is associated with lymph node metastasis and poor prognosis of colorectal cancer.
Submit: New GeneRIF Correction See all GeneRIFs (35)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Compton-North congenital myopathy
MedGen: C2675527 OMIM: 612540 GeneReviews: Not available
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EBI GWAS Catalog

Description
A genome-wide association study identifies protein quantitative trait loci (pQTLs).
EBI GWAS Catalog
A genome-wide association study identifies susceptibility loci of silica related pneumoconiosis in Han Chinese.
EBI GWAS Catalog
A genome-wide association study of seasonal pattern mania identifies NF1A as a possible susceptibility gene for bipolar disorder.
EBI GWAS Catalog
Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study.
EBI GWAS Catalog
Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes.
EBI GWAS Catalog
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
enables cell-cell adhesion mediator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in axon guidance IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in brain development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell adhesion NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in central nervous system myelin formation IEA
Inferred from Electronic Annotation
more info
  
involved_in cerebellum development IEA
Inferred from Electronic Annotation
more info
  
involved_in gene expression IEA
Inferred from Electronic Annotation
more info
  
involved_in locomotory behavior IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of neuron projection development IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of sodium ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular exosome HDA PubMed 
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
  
located_in membrane TAS
Traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
  
located_in presynaptic membrane IEA
Inferred from Electronic Annotation
more info
  
located_in side of membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
contactin-1
Names
glycoprotein gP135
neural cell surface protein F3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012058.2 RefSeqGene

    Range
    4884..384860
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001256063.2 → NP_001242992.1  contactin-1 isoform 3 precursor

    See identical proteins and their annotated locations for NP_001242992.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks several 3' exons and includes an alternate 3' terminal exon, compared to variant 1. The resulting isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1. Variants 3 and 4 encode the same isoform 3.
    Source sequence(s)
    AC015540, AC074030, AK289698, BC036569, DQ442054
    Consensus CDS
    CCDS58225.1
    UniProtKB/Swiss-Prot
    Q12860
    Related
    ENSP00000448004.1, ENST00000547702.5
    Conserved Domains (6) summary
    cd05727
    Location:134 → 230
    Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins
    cd05849
    Location:40 → 132
    Ig1_Contactin-1; First immunoglobulin (Ig) domain of contactin-1
    cd05851
    Location:241 → 328
    Ig3_Contactin-1; Third immunoglobulin (Ig) domain of contactin-1
    cd05852
    Location:429 → 501
    Ig5_Contactin-1; Fifth immunoglobulin (Ig) domain of contactin-1
    cd04970
    Location:520 → 602
    Ig6_Contactin; Sixth immunoglobulin (Ig) domain of contactin
    cl11960
    Location:332 → 408
    Ig; Immunoglobulin domain

  2. NM_001256064.2 → NP_001242993.1  contactin-1 isoform 3 precursor

    See identical proteins and their annotated locations for NP_001242993.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, lacks several 3' exons and includes an alternate 3' terminal exon, compared to variant 1. The resulting isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1. Variants 3 and 4 encode the same isoform 3.
    Source sequence(s)
    AC015540, AK289544
    Consensus CDS
    CCDS58225.1
    UniProtKB/Swiss-Prot
    Q12860
    Related
    ENSP00000448653.1, ENST00000547849.6
    Conserved Domains (6) summary
    cd05727
    Location:134 → 230
    Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins
    cd05849
    Location:40 → 132
    Ig1_Contactin-1; First immunoglobulin (Ig) domain of contactin-1
    cd05851
    Location:241 → 328
    Ig3_Contactin-1; Third immunoglobulin (Ig) domain of contactin-1
    cd05852
    Location:429 → 501
    Ig5_Contactin-1; Fifth immunoglobulin (Ig) domain of contactin-1
    cd04970
    Location:520 → 602
    Ig6_Contactin; Sixth immunoglobulin (Ig) domain of contactin
    cl11960
    Location:332 → 408
    Ig; Immunoglobulin domain

  3. NM_001843.4 → NP_001834.2  contactin-1 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001834.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) is the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC024900, AC074030, AI473107, AK289698, BM717031, BX648591, BY799936, DQ442054, U07819, Z21488
    Consensus CDS
    CCDS8737.1
    UniProtKB/Swiss-Prot
    A8K0H9, A8K0Y3, Q12860, Q12861, Q14030, Q7M4P0, Q8N466
    Related
    ENSP00000447006.1, ENST00000551295.7
    Conserved Domains (10) summary
    cd04970
    Location:520 → 601
    Ig6_Contactin_like; Sixth Ig domain of contactin
    cd05727
    Location:134 → 230
    Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins
    cd05849
    Location:40 → 132
    Ig1_Contactin-1; First Ig domain of contactin-1
    cd05851
    Location:241 → 328
    Ig3_Contactin-1; Third Ig domain of contactin-1
    cd05852
    Location:429 → 501
    Ig5_Contactin-1; Fifth Ig domain of contactin-1
    smart00410
    Location:422 → 501
    IG_like; Immunoglobulin like
    cd00063
    Location:610 → 697
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:331 → 408
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:811 → 893
    fn3; Fibronectin type III domain
    cl11960
    Location:332 → 408
    Ig; Immunoglobulin domain

  4. NM_175038.2 → NP_778203.1  contactin-1 isoform 2 precursor

    See identical proteins and their annotated locations for NP_778203.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an in-frame coding exon, compared to variant 1. The resulting isoform (2) lacks an internal segment in the N-terminal region, compared to isoform 1.
    Source sequence(s)
    AI473107, BC036569, BM717031, BX648591, BY799936, U07820
    Consensus CDS
    CCDS8738.1
    UniProtKB/Swiss-Prot
    Q12860
    Related
    ENSP00000261160.3, ENST00000348761.2
    Conserved Domains (10) summary
    cd04970
    Location:509 → 590
    Ig6_Contactin_like; Sixth Ig domain of contactin
    cd05727
    Location:123 → 219
    Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins
    cd05849
    Location:29 → 121
    Ig1_Contactin-1; First Ig domain of contactin-1
    cd05851
    Location:230 → 317
    Ig3_Contactin-1; Third Ig domain of contactin-1
    cd05852
    Location:418 → 490
    Ig5_Contactin-1; Fifth Ig domain of contactin-1
    smart00410
    Location:411 → 490
    IG_like; Immunoglobulin like
    cd00063
    Location:599 → 686
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:320 → 397
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:800 → 882
    fn3; Fibronectin type III domain
    cl11960
    Location:321 → 397
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    40692439..41072415
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011537926.4 → XP_011536228.1  contactin-1 isoform X1

    See identical proteins and their annotated locations for XP_011536228.1

    UniProtKB/Swiss-Prot
    A8K0H9, A8K0Y3, Q12860, Q12861, Q14030, Q7M4P0, Q8N466
    Conserved Domains (10) summary
    cd04970
    Location:520 → 601
    Ig6_Contactin_like; Sixth Ig domain of contactin
    cd05727
    Location:134 → 230
    Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins
    cd05849
    Location:40 → 132
    Ig1_Contactin-1; First Ig domain of contactin-1
    cd05851
    Location:241 → 328
    Ig3_Contactin-1; Third Ig domain of contactin-1
    cd05852
    Location:429 → 501
    Ig5_Contactin-1; Fifth Ig domain of contactin-1
    smart00410
    Location:422 → 501
    IG_like; Immunoglobulin like
    cd00063
    Location:610 → 697
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:331 → 408
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:811 → 893
    fn3; Fibronectin type III domain
    cl11960
    Location:332 → 408
    Ig; Immunoglobulin domain

  2. XM_024448843.2 → XP_024304611.1  contactin-1 isoform X2

    Conserved Domains (6) summary
    cd05727
    Location:134 → 230
    Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins
    cd05849
    Location:40 → 132
    Ig1_Contactin-1; First immunoglobulin (Ig) domain of contactin-1
    cd05851
    Location:241 → 328
    Ig3_Contactin-1; Third immunoglobulin (Ig) domain of contactin-1
    cd05852
    Location:429 → 501
    Ig5_Contactin-1; Fifth immunoglobulin (Ig) domain of contactin-1
    cd04970
    Location:520 → 602
    Ig6_Contactin; Sixth immunoglobulin (Ig) domain of contactin
    cl11960
    Location:332 → 408
    Ig; Immunoglobulin domain

  3. XM_005268651.3 → XP_005268708.1  contactin-1 isoform X1

    See identical proteins and their annotated locations for XP_005268708.1

    UniProtKB/Swiss-Prot
    A8K0H9, A8K0Y3, Q12860, Q12861, Q14030, Q7M4P0, Q8N466
    Related
    ENSP00000325660.3, ENST00000347616.5
    Conserved Domains (10) summary
    cd04970
    Location:520 → 601
    Ig6_Contactin_like; Sixth Ig domain of contactin
    cd05727
    Location:134 → 230
    Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins
    cd05849
    Location:40 → 132
    Ig1_Contactin-1; First Ig domain of contactin-1
    cd05851
    Location:241 → 328
    Ig3_Contactin-1; Third Ig domain of contactin-1
    cd05852
    Location:429 → 501
    Ig5_Contactin-1; Fifth Ig domain of contactin-1
    smart00410
    Location:422 → 501
    IG_like; Immunoglobulin like
    cd00063
    Location:610 → 697
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:331 → 408
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:811 → 893
    fn3; Fibronectin type III domain
    cl11960
    Location:332 → 408
    Ig; Immunoglobulin domain

  4. XM_011537927.3 → XP_011536229.1  contactin-1 isoform X1

    See identical proteins and their annotated locations for XP_011536229.1

    UniProtKB/Swiss-Prot
    A8K0H9, A8K0Y3, Q12860, Q12861, Q14030, Q7M4P0, Q8N466
    Conserved Domains (10) summary
    cd04970
    Location:520 → 601
    Ig6_Contactin_like; Sixth Ig domain of contactin
    cd05727
    Location:134 → 230
    Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins
    cd05849
    Location:40 → 132
    Ig1_Contactin-1; First Ig domain of contactin-1
    cd05851
    Location:241 → 328
    Ig3_Contactin-1; Third Ig domain of contactin-1
    cd05852
    Location:429 → 501
    Ig5_Contactin-1; Fifth Ig domain of contactin-1
    smart00410
    Location:422 → 501
    IG_like; Immunoglobulin like
    cd00063
    Location:610 → 697
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:331 → 408
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:811 → 893
    fn3; Fibronectin type III domain
    cl11960
    Location:332 → 408
    Ig; Immunoglobulin domain

  5. XM_006719241.3 → XP_006719304.1  contactin-1 isoform X1

    See identical proteins and their annotated locations for XP_006719304.1

    UniProtKB/Swiss-Prot
    A8K0H9, A8K0Y3, Q12860, Q12861, Q14030, Q7M4P0, Q8N466
    Conserved Domains (10) summary
    cd04970
    Location:520 → 601
    Ig6_Contactin_like; Sixth Ig domain of contactin
    cd05727
    Location:134 → 230
    Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins
    cd05849
    Location:40 → 132
    Ig1_Contactin-1; First Ig domain of contactin-1
    cd05851
    Location:241 → 328
    Ig3_Contactin-1; Third Ig domain of contactin-1
    cd05852
    Location:429 → 501
    Ig5_Contactin-1; Fifth Ig domain of contactin-1
    smart00410
    Location:422 → 501
    IG_like; Immunoglobulin like
    cd00063
    Location:610 → 697
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:331 → 408
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:811 → 893
    fn3; Fibronectin type III domain
    cl11960
    Location:332 → 408
    Ig; Immunoglobulin domain

  6. XM_017018827.3 → XP_016874316.1  contactin-1 isoform X2

    UniProtKB/Swiss-Prot
    Q12860
    Conserved Domains (6) summary
    cd05727
    Location:134 → 230
    Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins
    cd05849
    Location:40 → 132
    Ig1_Contactin-1; First immunoglobulin (Ig) domain of contactin-1
    cd05851
    Location:241 → 328
    Ig3_Contactin-1; Third immunoglobulin (Ig) domain of contactin-1
    cd05852
    Location:429 → 501
    Ig5_Contactin-1; Fifth immunoglobulin (Ig) domain of contactin-1
    cd04970
    Location:520 → 602
    Ig6_Contactin; Sixth immunoglobulin (Ig) domain of contactin
    cl11960
    Location:332 → 408
    Ig; Immunoglobulin domain

  7. XM_017018826.3 → XP_016874315.1  contactin-1 isoform X2

    UniProtKB/Swiss-Prot
    Q12860
    Conserved Domains (6) summary
    cd05727
    Location:134 → 230
    Ig2_Contactin-2-like; Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins
    cd05849
    Location:40 → 132
    Ig1_Contactin-1; First immunoglobulin (Ig) domain of contactin-1
    cd05851
    Location:241 → 328
    Ig3_Contactin-1; Third immunoglobulin (Ig) domain of contactin-1
    cd05852
    Location:429 → 501
    Ig5_Contactin-1; Fifth immunoglobulin (Ig) domain of contactin-1
    cd04970
    Location:520 → 602
    Ig6_Contactin; Sixth immunoglobulin (Ig) domain of contactin
    cl11960
    Location:332 → 408
    Ig; Immunoglobulin domain

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    40652132..41031590
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054371130.1 → XP_054227105.1  contactin-1 isoform X1

    UniProtKB/Swiss-Prot
    A8K0H9, A8K0Y3, Q12860, Q12861, Q14030, Q7M4P0, Q8N466

  2. XM_054371133.1 → XP_054227108.1  contactin-1 isoform X2

  3. XM_054371131.1 → XP_054227106.1  contactin-1 isoform X1

    UniProtKB/Swiss-Prot
    A8K0H9, A8K0Y3, Q12860, Q12861, Q14030, Q7M4P0, Q8N466

  4. XM_054371132.1 → XP_054227107.1  contactin-1 isoform X1

    UniProtKB/Swiss-Prot
    A8K0H9, A8K0Y3, Q12860, Q12861, Q14030, Q7M4P0, Q8N466

  5. XM_054371129.1 → XP_054227104.1  contactin-1 isoform X1

    UniProtKB/Swiss-Prot
    A8K0H9, A8K0Y3, Q12860, Q12861, Q14030, Q7M4P0, Q8N466

  6. XM_054371135.1 → XP_054227110.1  contactin-1 isoform X2

  7. XM_054371134.1 → XP_054227109.1  contactin-1 isoform X2

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12860.1 GenPept UniProtKB/Swiss-Prot:Q12860

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