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LOC126860528 P300/CBP strongly-dependent group 1 enhancer GRCh37_chr8:134194436-134195635 [ Homo sapiens (human) ]

Gene ID: 126860528, updated on 12-Sep-2024

Summary

Gene symbol
LOC126860528
Gene description
P300/CBP strongly-dependent group 1 enhancer GRCh37_chr8:134194436-134195635
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the STARR-seq (self-transcribing active regulatory region sequencing) massively parallel reporter assay in HCT116 colorectal carcinoma cells. This sequence was defined as a group 1 enhancer that depends on the BRD2, BRD4, P300/CBP, MED14 and CDK7 cofactors, with strong dependence on P300/CBP. [provided by RefSeq, Sep 2022]
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Genomic context

See LOC126860528 in Genome Data Viewer
Location:
chromosome: 8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (133182192..133183391)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (134305515..134306714)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (134194436..134195635)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene thyroglobulin Neighboring gene Src like adaptor Neighboring gene papillary thyroid carcinoma susceptibility candidate 1 Neighboring gene uncharacterized LOC105375769 Neighboring gene NANOG hESC enhancer GRCh37_chr8:134157066-134157567 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:134204154-134204401 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:134208271-134208770 Neighboring gene uncharacterized LOC102723635 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr8:134224019-134225218 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19560 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr8:134229946-134231145 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:134234981-134235482 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27993 Neighboring gene cellular communication network factor 4 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr8:134259869-134261068 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19561 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:134272289-134272788 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:134277906-134278406 Neighboring gene N-myc downstream regulated 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:134297442-134297942 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr8:134305980-134307179 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19562

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_085028.1 

    Range
    101..1300
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    133182192..133183391
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    134305515..134306714
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    GenBank, FASTA, Sequence Viewer (Graphics)