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LOC126860078 MED14-independent group 3 enhancer GRCh37_chr7:77619182-77620381 [ Homo sapiens (human) ]

Gene ID: 126860078, updated on 12-Sep-2024

Summary

Gene symbol
LOC126860078
Gene description
MED14-independent group 3 enhancer GRCh37_chr7:77619182-77620381
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the STARR-seq (self-transcribing active regulatory region sequencing) massively parallel reporter assay in HCT116 colorectal carcinoma cells. This sequence was defined as a group 3 enhancer that depends on the BRD2, BRD4, P300/CBP and CDK7 cofactors, but it has limited or no dependence on the MED14 core Mediator complex subunit. [provided by RefSeq, Sep 2022]
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Genomic context

See LOC126860078 in Genome Data Viewer
Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (77989865..77991064)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (79241720..79242919)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (77619182..77620381)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26208 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18330 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26209 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18331 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:77464234-77464734 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:77501601-77502172 Neighboring gene uncharacterized LOC124901682 Neighboring gene transmembrane protein 60 Neighboring gene putative homeodomain transcription factor 2 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr7:77635196-77635696 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:77648359-77648860 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18332 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18333 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:77677051-77677551 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:77703601-77704220 Neighboring gene DDX3 interacting lncRNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:77763787-77764288 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:77764289-77764788 Neighboring gene membrane associated guanylate kinase, WW and PDZ domain containing 2 Neighboring gene uncharacterized LOC124901684 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:77875627-77876563 Neighboring gene ribosomal protein L13a pseudogene 17

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_084579.1 

    Range
    101..1300
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    77989865..77991064
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    79241720..79242919
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    GenBank, FASTA, Sequence Viewer (Graphics)