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PRADX PRC2 and DDX5 associated lncRNA [ Homo sapiens (human) ]

Gene ID: 126568849, updated on 28-Oct-2024

Summary

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Official Symbol
PRADXprovided by HGNC
Official Full Name
PRC2 and DDX5 associated lncRNAprovided by HGNC
Primary source
HGNC:HGNC:40168
See related
Ensembl:ENSG00000235027 AllianceGenome:HGNC:40168
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
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Genomic context

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See PRADX in Genome Data Viewer
Location:
11p15.5
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (1760348..1762486)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (1846008..1848146)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (1781578..1783716)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene keratin associated protein 5-6 Neighboring gene interferon induced transmembrane protein 10 Neighboring gene skeletal muscle cis-regulatory module in IFITM10 intron Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:1770125-1770880 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:1770881-1771636 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3057 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3058 Neighboring gene cathepsin D Neighboring gene uncharacterized LOC105376517 Neighboring gene uncharacterized LOC124902610 Neighboring gene ribosomal protein L36a pseudogene 39

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. lncRNA PRADX is a Mesenchymal Glioblastoma Biomarker for Cellular Metabolism Targeted Therapy. Xu C, et al. Front Oncol, 2022. PMID 35574370, Free PMC Article
  2. LncRNA PRADX-mediated recruitment of PRC2/DDX5 complex suppresses UBXN1 expression and activates NF-κB activity, promoting tumorigenesis. Li Y, et al. Theranostics, 2021. PMID 33754075, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

General gene information

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Clone Names

  • DKFZp313C0323

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_182291.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC068580
    Related
    ENST00000449248.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    1760348..1762486
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    1846008..1848146
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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