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Gcnt4 glucosaminyl (N-acetyl) transferase 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 120100673, updated on 27-Nov-2024

Summary

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Symbol
Gcnt4provided by RGD
Full Name
glucosaminyl (N-acetyl) transferase 4provided by RGD
Primary source
RGD:1563891
See related
EnsemblRapid:ENSRNOG00000064612 AllianceGenome:RGD:1563891
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1563891
Summary
Predicted to enable glycosyltransferase activity. Predicted to act upstream of or within several processes, including inter-male aggressive behavior; neutrophil homeostasis; and thyroid hormone metabolic process. Predicted to be located in Golgi membrane. Orthologous to human GCNT4 (glucosaminyl (N-acetyl) transferase 4). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See Gcnt4 in Genome Data Viewer
Location:
2q12
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (29987944..30017708)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (28253325..28283082)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 31 Neighboring gene chromobox 3, pseudogene 1 Neighboring gene RNA, U6 small nuclear 180 Neighboring gene uncharacterized LOC134485580 Neighboring gene uncharacterized LOC134485579

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Glycosyltransferase function in core 2-type protein O glycosylation. Stone EL, et al. Mol Cell Biol, 2009 Jul. PMID 19349303, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables acetylglucosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within inter-male aggressive behavior ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within kidney morphogenesis ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within neutrophil homeostasis ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within thyroid hormone metabolic process ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within tissue morphogenesis ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4
Names
glucosaminyl (N-acetyl) transferase 4, core 2
NP_001386718.1
XP_038959395.1
XP_038959396.1
XP_038959397.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399789.1 → NP_001386718.1  beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    A0A8I6ARU0
    Related
    ENSRNOP00000107944.1, ENSRNOT00000130921.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    29987944..30017708
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039103467.2 → XP_038959395.1  beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 isoform X1

    UniProtKB/TrEMBL
    A0A8I6ARU0
    Related
    ENSRNOP00000095630.1, ENSRNOT00000107684.2
    Conserved Domains (1) summary
    cl27418
    Location:134 → 403
    Branch; Core-2/I-Branching enzyme

  2. XM_039103468.2 → XP_038959396.1  beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 isoform X1

    UniProtKB/TrEMBL
    A0A8I6ARU0
    Related
    ENSRNOP00000103608.1, ENSRNOT00000156906.1
    Conserved Domains (1) summary
    cl27418
    Location:134 → 403
    Branch; Core-2/I-Branching enzyme

  3. XM_039103469.2 → XP_038959397.1  beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 isoform X1

    UniProtKB/TrEMBL
    A0A8I6ARU0
    Related
    ENSRNOP00000111631.1, ENSRNOT00000155971.1
    Conserved Domains (1) summary
    cl27418
    Location:134 → 403
    Branch; Core-2/I-Branching enzyme
Nucleotide Protein Strain
Heading Accession and Version

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