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Fer FER tyrosine kinase [ Rattus rattus (black rat) ]

Gene ID: 116899691, updated on 18-Mar-2024

Summary

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Gene symbol
Fer
Gene description
FER tyrosine kinase
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus rattus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Orthologs
human mouse all
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Genomic context

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See Fer in Genome Data Viewer
Location:
chromosome: 4
Exon count:
18
Annotation release Status Assembly Chr Location
100 current Rrattus_CSIRO_v1 (GCF_011064425.1) 4 NC_046157.1 (173988298..174240354)

Chromosome 4 - NC_046157.1Genomic Context describing neighboring genes Neighboring gene tubulin alpha-1 chain-like Neighboring gene F-box and leucine rich repeat protein 17 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene U6 spliceosomal RNA Neighboring gene praja ring finger ubiquitin ligase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_046157.1 Chromosome 4 Reference Rrattus_CSIRO_v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel protein-tyrosine kinase cDNAs related to fps/fes and eph cloned using anti-phosphotyrosine antibody. Letwin K, et al. Oncogene, 1988 Dec. PMID 2485255
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Fc-epsilon receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mast cell degranulation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: tyrosine-protein kinase Fer
Names
flk protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rattus rattus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rrattus_CSIRO_v1 Primary Assembly

Genomic

  1. NC_046157.1 Reference Rrattus_CSIRO_v1 Primary Assembly

    Range
    173988298..174240354
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032901714.1 → XP_032757605.1  LOW QUALITY PROTEIN: tyrosine-protein kinase Fer

    Conserved Domains (3) summary
    cd07686
    Location:5 → 238
    F-BAR_Fer; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Fer (Fes related) tyrosine kinase
    cd10361
    Location:454 → 539
    SH2_Fps_family; Src homology 2 (SH2) domain found in feline sarcoma, Fujinami poultry sarcoma, and fes-related (Fes/Fps/Fer) proteins
    cl21453
    Location:567 → 817
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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