Pcdha10 protocadherin alpha 10 [Rattus norvegicus (Norway rat)] - Gene

Summary

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Official Symbol: Pcdha10provided by RGD
Official Full Name: protocadherin alpha 10provided by RGD
Primary source: RGD:620749
See related: AllianceGenome:RGD:620749
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: rCNRv10
Summary: Predicted to act upstream of or within aorta development; aortic valve development; and gene expression. Predicted to be located in membrane. Predicted to be active in cell-cell contact zone. Orthologous to human PCDHA10 (protocadherin alpha 10). [provided by Alliance of Genome Resources, Jan 2025]
Annotation information: not in current annotation release
Expression: Biased expression in Brain (RPKM 141.4), Lung (RPKM 100.5) and 7 other tissues See more
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Genomic context

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See Pcdha10 in Genome Data Viewer

Location:: 18p11

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

BF389688 (e-PCR)
- UniSTS:245509

PMC312645P1 (e-PCR)
- UniSTS:272906

RH91795 (e-PCR)
- UniSTS:85819

IB766 (e-PCR)
- UniSTS:42573

WI-19540 (e-PCR)
- UniSTS:63886

NoName (e-PCR)
- UniSTS:547524

Pcdha (e-PCR), detects polymorphism
- UniSTS:547524

RH65516 (e-PCR)
- UniSTS:66009

PMC311048P1 (e-PCR)
- UniSTS:272867

PMC311048P3 (e-PCR)
- UniSTS:272869

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
acts_upstream_of_or_within aorta development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within aortic valve development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within gene expression	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within heart development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within heart valve development	ISO Inferred from Sequence Orthology more info
involved_in spermatogenesis	NAS Non-traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
is_active_in cell-cell contact zone	ISO Inferred from Sequence Orthology more info
located_in membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: protocadherin alpha-10

Names: cadherin-related neuronal receptor 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_053939.2 → NP_446391.1 protocadherin alpha-10

See identical proteins and their annotated locations for NP_446391.1

Status: VALIDATED

Source sequence(s)

JACYVU010000299

UniProtKB/TrEMBL

Q767I2

Conserved Domains (3) summary

cd11304
Location:276 → 376

Cadherin_repeat; Cadherin tandem repeat domain

pfam08266
Location:60 → 141

Cadherin_2; Cadherin-like

pfam15974
Location:828 → 971

Cadherin_tail; Cadherin C-terminal cytoplasmic tail, catenin-binding region