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pklr - pyruvate kinase L/R

Predicted to enable pyruvate kinase activity. Acts upstream of or within liver development. Predicted to be active in cytoplasm. Is expressed in digestive system; female organism; heart; male organism; and muscle. Human ortholog(s) of this gene implicated in Gaucher's disease; congenital nonspherocytic hemolytic anemia; malaria; pyruvate kinase deficiency of red cells; and type 2 diabetes mellitus. Orthologous to human PKLR (pyruvate kinase L/R). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa