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Mir497b microRNA mir-497b [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 114483827, updated on 18-Jul-2023

Summary

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Gene symbol
Mir497b
Gene description
microRNA mir-497b
See related
Ensembl:ENSCGRG00015006759 miRBase:MI0033095
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Also known as
cgr-mir-497b
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

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See Mir497b in Genome Data Viewer
Location:
chromosome: 7
Exon count:
1
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613643.1 (2276413..2276537, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 7 NC_048600.1 (84059657..84059781, complement)

NW_003613643.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 16 member 11 Neighboring gene solute carrier family 16 member 13 Neighboring gene BCL6B transcription repressor Neighboring gene microRNA mir-497 Neighboring gene microRNA mir-195 Neighboring gene BPTF associated chromatin complex component 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of additional evolutionary conserved microRNAs in CHO cells from updated genomic data. Diendorfer AB, et al. Biotechnol Bioeng, 2015 Jul. PMID 25689160, Free PMC Article
  2. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_162767.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AFTD01015315
    Related
    ENSCGRT00015010719.2

RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613643.1 Reference CriGri_1.0 Primary Assembly

    Range
    2276413..2276537 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048600.1 Alternate CriGri-PICRH-1.0

    Range
    84059657..84059781 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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