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prdm1b - PR domain containing 1b, with ZNF domain

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; metal ion binding activity; and methyltransferase activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cellular developmental process and methylation. Is expressed in retina and somite. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and lung adenocarcinoma. Orthologous to human PRDM1 (PR/SET domain 1). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa