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LOC109279840 Fgfr1 promoter region [ Mus musculus (house mouse) ]

Gene ID: 109279840, updated on 9-Aug-2024

Summary

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Gene symbol
LOC109279840
Gene description
Fgfr1 promoter region
Gene type
biological region
Feature type(s)
protein_bind
regulatory: promoter, response_element
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rr366769
Summary
This region represents the promoter of the fibroblast growth factor receptor 1 gene. This promoter is stimulated by thyroid hormone through a discrete response element, and is also regulated by Sp1/Sp3 transcription factors. [provided by RefSeq, Dec 2016]
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Genomic context

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See LOC109279840 in Genome Data Viewer
Location:
chromosome: 8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (26007940..26008914)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (25517924..25518898)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene 10689 Neighboring gene predicted gene, 31045 Neighboring gene predicted gene, 31288 Neighboring gene fibroblast growth factor receptor 1 Neighboring gene VISTA enhancer mm612 Neighboring gene STARR-seq mESC enhancer starr_20978 Neighboring gene predicted gene 16159

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation of fibroblast growth factor receptor-1 (FGFR1) by thyroid hormone: identification of a thyroid hormone response element in the murine Fgfr1 promoter. O'Shea PJ, et al. Endocrinology, 2007 Dec. PMID 17761769
  2. Sp1 is required for transcriptional activation of the fibroblast growth factor receptor 1 gene in neonatal cardiomyocytes. Seyed M, et al. Gene, 2007 Oct 1. PMID 17628354
  3. Mapping of a transcription element critical for expression of the fibroblast growth factor receptor 1 gene. Saito H, et al. Biochem Biophys Res Commun, 1994 Feb 15. PMID 8117257
  4. Characterization of the promoter region of the murine fibroblast growth factor receptor 1 gene. Saito H, et al. Biochem Biophys Res Commun, 1992 Mar 16. PMID 1312839
  5. Fibroblast growth factor receptor 1 gene expression is required for cardiomyocyte proliferation and is repressed by Sp3. Seyed M, et al. J Mol Cell Cardiol, 2008 Mar. PMID 18275970

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • regulatory region 366769

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_052555.1 

    Range
    101..1075
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    26007940..26008914
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Research Materials