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Ifne interferon, epsilon [ Rattus norvegicus (Norway rat) ]

Gene ID: 108350996, updated on 27-Nov-2024

Summary

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Symbol
Ifneprovided by RGD
Full Name
interferon, epsilonprovided by RGD
Primary source
RGD:1565065
See related
EnsemblRapid:ENSRNOG00000024204 AllianceGenome:RGD:1565065
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
If1ea; RGD1565065
Summary
Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including defense response to other organism; lymphocyte activation involved in immune response; and positive regulation of receptor signaling pathway via JAK-STAT. Predicted to be active in extracellular space. Orthologous to human IFNE (interferon epsilon). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See Ifne in Genome Data Viewer
Location:
5q32
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (108687443..108688103, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (103571630..103572290, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (107178124..107203908)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene interferon, alpha 4 like 1 Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC130062807 Neighboring gene microRNA 3554 Neighboring gene microRNA 31 Neighboring gene uncharacterized LOC130062808

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Interferon-ε protects the female reproductive tract from viral and bacterial infection. Fung KY, et al. Science, 2013 Mar 1. PMID 23449591, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in defense response to bacterium ISO
Inferred from Sequence Orthology
more info
  
involved_in defense response to virus ISO
Inferred from Sequence Orthology
more info
  
involved_in natural killer cell activation ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of receptor signaling pathway via JAK-STAT ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
interferon epsilon
Names
interferon 1ea

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001402768.1 → NP_001389697.1  interferon epsilon

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    A0A7R8GUU9
    Related
    ENSRNOP00000031172.8, ENSRNOT00000029976.8

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    108687443..108688103 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.