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LOC107966122 D6 enhancer downstream of Sox10 [ Mus musculus (house mouse) ]

Gene ID: 107966122, updated on 9-Aug-2024

Summary

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Gene symbol
LOC107966122
Gene description
D6 enhancer downstream of Sox10
Gene type
biological region
Feature type(s)
protein_bind
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D6; Rr366666
Summary
This region represents a conserved enhancer located approximately 12 kb downstream of the SRY-box 10 (Sox10) promoter. This sequence drives expression of a transgene in the ganglia and otic vesicle. [provided by RefSeq, Sep 2016]
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Genomic context

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See LOC107966122 in Genome Data Viewer
Location:
chromosome: 15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (79036804..79037385)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (79152604..79153185)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene microtubule associated monooxygenase, calponin and LIM domain containing -like 1 Neighboring gene RIKEN cDNA 1700088E04 gene Neighboring gene STARR-positive B cell enhancer ABC_E7388 Neighboring gene polymerase (RNA) II (DNA directed) polypeptide F Neighboring gene MCS1C/MCS2 enhancer region 5' of Sox10 Neighboring gene SRY (sex determining region Y)-box 10 Neighboring gene predicted gene 10863 Neighboring gene predicted gene, 53902

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genomic code for Sox10 activation reveals a key regulatory enhancer for cranial neural crest. Betancur P, et al. Proc Natl Acad Sci U S A, 2010 Feb 23. PMID 20139305, Free PMC Article
  2. Multiple conserved regulatory elements with overlapping functions determine Sox10 expression in mouse embryogenesis. Werner T, et al. Nucleic Acids Res, 2007. PMID 17897962, Free PMC Article
  3. Distant regulatory elements in a Sox10-beta GEO BAC transgene are required for expression of Sox10 in the enteric nervous system and other neural crest-derived tissues. Deal KK, et al. Dev Dyn, 2006 May. PMID 16586440

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • regulatory region 366666

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_050694.1 

    Range
    101..682
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    79036804..79037385
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version