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Mfcs4 mammal fish conserved sequence 4 [ Mus musculus (house mouse) ]

Gene ID: 106050034, updated on 9-Aug-2024

Summary

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Gene symbol
Mfcs4
Gene description
mammal fish conserved sequence 4
Gene type
biological region
Feature type(s)
misc_feature: conserved_region
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rr366631
Summary
This region contains a highly conserved sequence that functions as an enhancer in the pharyngeal epithelium. This sequence may regulate expression of the sonic hedgehog (Shh) gene, located approximately 720 kb downstream. [provided by RefSeq, Sep 2016]
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Genomic context

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See Mfcs4 in Genome Data Viewer
Location:
chromosome: 5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (29392493..29393491)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (29187495..29188493)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 35688 Neighboring gene Shh brain enhancer 3 Neighboring gene STARR-seq mESC enhancer starr_12726 Neighboring gene predicted gene, 35881 Neighboring gene STARR-seq mESC enhancer starr_12727 Neighboring gene mammal reptile conserved sequence 1 Neighboring gene STARR-seq mESC enhancer starr_12728 Neighboring gene mammal fish conserved sequence 3 Neighboring gene STARR-seq mESC enhancer starr_12729 Neighboring gene ring finger protein 32 Neighboring gene predicted gene 7420 Neighboring gene mammal amphibian conserved sequence 1 Neighboring gene limb region 1 Neighboring gene STARR-seq mESC enhancer starr_12732 Neighboring gene STARR-seq mESC enhancer starr_12733 Neighboring gene STARR-seq mESC enhancer starr_12734 Neighboring gene STARR-positive B cell enhancer ABC_E9634 Neighboring gene zone of polarising activity regulatory sequence 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Highly conserved non-coding sequences are associated with vertebrate development. Woolfe A, et al. PLoS Biol, 2005 Jan. PMID 15630479, Free PMC Article
  2. Long range regulation of the sonic hedgehog gene. Anderson E, et al. Curr Opin Genet Dev, 2014 Aug. PMID 24859115
  3. A cluster of three long-range enhancers directs regional Shh expression in the epithelial linings. Sagai T, et al. Development, 2009 May. PMID 19369396

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • regulatory region 366631

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_042260.1 

    Range
    101..1099
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    29392493..29393491
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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