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SPPL2B signal peptide peptidase like 2B [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105591881, updated on 13-Mar-2024

Summary

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Gene symbol
SPPL2B
Gene description
signal peptide peptidase like 2B
See related
Ensembl:ENSCATG00000037765
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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See SPPL2B in Genome Data Viewer
Location:
chromosome: Un
Exon count:
14
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012001295.1 (2178313..2201423)

NW_012001295.1Genomic Context describing neighboring genes Neighboring gene PEAK family member 3 Neighboring gene leucine rich repeat and Ig domain containing 3 Neighboring gene LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated Neighboring gene transmembrane serine protease 9 Neighboring gene translocase of inner mitochondrial membrane 13

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012001295.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic endopeptidase activity, intramembrane cleaving IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in membrane protein proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi-associated vesicle membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasmic side of endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lumenal side of endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal peptide peptidase-like 2B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012001295.1 Reference Caty_1.0

    Range
    2178313..2201423
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012073299.1 → XP_011928689.1  signal peptide peptidase-like 2B

    UniProtKB/TrEMBL
    A0A2K5MUU1
    Related
    ENSCATP00000028997.1, ENSCATT00000053252.1
    Conserved Domains (2) summary
    cd02129
    Location:71 → 190
    PA_hSPPL_like; PA_hSPPL_like: Protease-associated domain containing human signal peptide peptidase-like (hSPPL)-like. This group contains various PA domain-containing proteins similar to hSPPL2a and 2b. These SPPLs are GxGD aspartic proteases. SPPL2a is sorted to the ...
    pfam04258
    Location:240 → 593
    Peptidase_A22B; Signal peptide peptidase
Nucleotide Protein
Heading Accession and Version

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