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klf10 Kruppel like factor 10 [ Danio rerio (zebrafish) ]

Gene ID: 103908991, updated on 2-Nov-2024

Summary

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Official Symbol
klf10provided by ZNC
Official Full Name
Kruppel like factor 10provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-2991
See related
AllianceGenome:ZFIN:ZDB-GENE-030131-2991
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc23d01; wu:fc23d01
Summary
Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be involved in anatomical structure morphogenesis. Orthologous to human KLF10 (KLF transcription factor 10). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See klf10 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (52665020..52669377)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (52779262..52783642)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene serine and arginine rich splicing factor 10a Neighboring gene ubiquitin protein ligase E3 component n-recognin 5 Neighboring gene uncharacterized LOC137487993 Neighboring gene serine/threonine-protein kinase pim-2-like Neighboring gene uncharacterized LOC137487995

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Age-dependent expression changes of circadian system-related genes reveal a potentially conserved link to aging. Barth E, et al. Aging (Albany NY), 2021 Dec 19. PMID 34923482, Free PMC Article
  2. Characterization and phylogenetic analysis of Krüppel-like transcription factor (KLF) gene family in tree shrews (Tupaia belangeri chinensis). Shao M, et al. Oncotarget, 2017 Mar 7. PMID 28032601, Free PMC Article
  3. Partial depletion of yolk during zebrafish embryogenesis changes the dynamics of methionine cycle and metabolic genes. Huang Y, et al. BMC Genomics, 2015 Jun 4. PMID 26040990, Free PMC Article
  4. Genome-wide analysis of the zebrafish Klf family identifies two genes important for erythroid maturation. Xue Y, et al. Dev Biol, 2015 Jul 15. PMID 26015096
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in anatomical structure morphogenesis IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Kruppel-like factor 10
Names
Krueppel-like factor 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001386438.1 → NP_001373367.1  Kruppel-like factor 10

    Status: VALIDATED

    Source sequence(s)
    CR524823
    UniProtKB/TrEMBL
    A0A8M3AIL2
    Conserved Domains (4) summary
    COG5048
    Location:96 → 179
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:122 → 141
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:163 → 188
    zf-H2C2_2; Zinc-finger double domain
    cl41731
    Location:2 → 117
    KLF10_11_N; N-terminal domain of Kruppel-like factor (KLF) 10, KLF11, and similar proteins

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    52665020..52669377
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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