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Nyap2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 103690221, updated on 27-Nov-2024

Summary

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Official Symbol
Nyap2provided by RGD
Official Full Name
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2provided by RGD
Primary source
RGD:9171458
See related
EnsemblRapid:ENSRNOG00000023765 AllianceGenome:RGD:9171458
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in neuron projection morphogenesis and phosphatidylinositol 3-kinase/protein kinase B signal transduction. Orthologous to human NYAP2 (neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward (RPKM 40.3) See more
Orthologs
human mouse all
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Genomic context

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See Nyap2 in Genome Data Viewer
Location:
9q34
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (89855109..90133466)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (82406797..82658250)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (86873942..87151060)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134480394 Neighboring gene uncharacterized LOC134480399 Neighboring gene uncharacterized LOC134480400 Neighboring gene uncharacterized LOC120094719 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. Yokoyama K, et al. EMBO J, 2011 Sep 23. PMID 21946561, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in neuron projection morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in neuron projection morphogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427707.1 → NP_001414636.1  neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    F1M3A4

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    89855109..90133466
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063266525.1 → XP_063122595.1  neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 isoform X1

  2. XM_063266527.1 → XP_063122597.1  neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 isoform X2

    UniProtKB/TrEMBL
    F1M3A4

  3. XM_063266530.1 → XP_063122600.1  neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 isoform X5

    Related
    ENSRNOP00000049039.5, ENSRNOT00000041337.7

  4. XM_063266526.1 → XP_063122596.1  neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 isoform X1

    Related
    ENSRNOP00000076966.2, ENSRNOT00000118397.2

  5. XM_063266528.1 → XP_063122598.1  neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 isoform X2

    UniProtKB/TrEMBL
    F1M3A4

  6. XM_063266529.1 → XP_063122599.1  neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 isoform X4

  7. XM_017596837.3 → XP_017452326.1  neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 isoform X3

    UniProtKB/TrEMBL
    A0A8I5ZZ68
Nucleotide Protein Strain
Heading Accession and Version

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