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Wdr90 WD repeat domain 90 [ Rattus norvegicus (Norway rat) ]

Gene ID: 102555298, updated on 27-Nov-2024

Summary

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Official Symbol
Wdr90provided by RGD
Official Full Name
WD repeat domain 90provided by RGD
Primary source
RGD:7520481
See related
EnsemblRapid:ENSRNOG00000020006 AllianceGenome:RGD:7520481
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1561785
Summary
Predicted to be involved in cilium assembly. Predicted to be located in centrosome. Predicted to be active in centriole. Orthologous to human WDR90 (WD repeat domain 90). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Adrenal (RPKM 47.6), Thymus (RPKM 38.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Wdr90 in Genome Data Viewer
Location:
10q12
Exon count:
41
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15369184..15385797, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (14864672..14881285, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (15211660..15229477, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene jumonji domain containing 8 Neighboring gene STIP1 homology and U-box containing protein 1 Neighboring gene rhomboid like 1 Neighboring gene ras homolog family member T2 Neighboring gene MAPK regulated co-repressor interacting protein 2 Neighboring gene methyltransferase like 26 Neighboring gene transfer RNA glycine (anticodon CCC) 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Identification of Chlamydomonas Central Core Centriolar Proteins Reveals a Role for Human WDR90 in Ciliogenesis. Hamel V, et al. Curr Biol, 2017 Aug 21. PMID 28781053, Free PMC Article
  2. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in cilium assembly ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in centriole IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in centriole ISO
Inferred from Sequence Orthology
more info
  
located_in centrosome IEA
Inferred from Electronic Annotation
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
WD repeat domain 90; WD repeat-containing protein 90
Names
WD repeat-containing protein 90-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001433408.1 → NP_001420337.1  WD repeat domain 90

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    15369184..15385797 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006246068.4 → XP_006246130.1  WD repeat-containing protein 90 isoform X2

    UniProtKB/TrEMBL
    D3ZMM2
    Related
    ENSRNOT00000027121.8
    Conserved Domains (4) summary
    COG2319
    Location:1256 → 1679
    WD40; WD40 repeat [General function prediction only]
    pfam05018
    Location:60 → 236
    DUF667; Protein of unknown function (DUF667)
    sd00039
    Location:1285 → 1327
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:758 → 1058
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_006246066.4 → XP_006246128.1  WD repeat-containing protein 90 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZMK6
    Conserved Domains (4) summary
    COG2319
    Location:1256 → 1679
    WD40; WD40 repeat [General function prediction only]
    pfam05018
    Location:60 → 236
    DUF667; Protein of unknown function (DUF667)
    sd00039
    Location:1285 → 1327
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:758 → 1058
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_039087116.1 → XP_038943044.1  WD repeat-containing protein 90 isoform X3

    Conserved Domains (3) summary
    COG2319
    Location:732 → 1155
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:761 → 803
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:234 → 534
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. XM_063270092.1 → XP_063126162.1  WD repeat-containing protein 90 isoform X4

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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