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Zfp120 zinc finger protein 120 [ Rattus norvegicus (Norway rat) ]

Gene ID: 102554315, updated on 4-Jan-2025

Summary

Official Symbol
Zfp120provided by RGD
Official Full Name
zinc finger protein 120provided by RGD
Primary source
RGD:7747897
See related
EnsemblRapid:ENSRNOG00000067071 AllianceGenome:RGD:7747897
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human ZNF490 (zinc finger protein 490). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Spleen (RPKM 79.9), Thymus (RPKM 69.5) and 9 other tissues See more
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Genomic context

See Zfp120 in Genome Data Viewer
Location:
3q41
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (159206172..159251493)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (138763244..138791042)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (145636480..145663908, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 442 Neighboring gene uncharacterized LOC134486179 Neighboring gene UPF0472 protein C16orf72 homolog pseudogene Neighboring gene ArfGAP with FG repeats 1, pseudogene 1 Neighboring gene RIKEN cDNA 3300002I08 gene like 1 Neighboring gene uncharacterized LOC102554820 Neighboring gene sperm motility kinase x like 3

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 120
Names
zinc finger protein 596-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001431867.1NP_001418796.1  zinc finger protein 120 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    A0A8I5Y958
  2. NM_001431868.1NP_001418797.1  zinc finger protein 120 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
  3. NM_001431869.1NP_001418798.1  zinc finger protein 120 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    159206172..159251493
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063285044.1XP_063141114.1  zinc finger protein 120 isoform X4

  2. XM_063285043.1XP_063141113.1  zinc finger protein 120 isoform X2

    Related
    ENSRNOP00000103282.1, ENSRNOT00000158597.1
  3. XM_006235189.5XP_006235251.1  zinc finger protein 120 isoform X1

    Related
    ENSRNOP00000076862.1, ENSRNOT00000104232.2
    Conserved Domains (5) summary
    smart00349
    Location:2869
    KRAB; krueppel associated box
    COG5048
    Location:51362
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:297317
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:2867
    KRAB; KRAB box
    pfam13465
    Location:337362
    zf-H2C2_2; Zinc-finger double domain
  4. XM_039106642.2XP_038962570.1  zinc finger protein 120 isoform X3

    Conserved Domains (2) summary
    sd00017
    Location:101121
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:2768
    KRAB; KRAB box
  5. XM_006235193.5XP_006235255.1  zinc finger protein 120 isoform X5

    Conserved Domains (2) summary
    smart00349
    Location:2875
    KRAB; krueppel associated box
    pfam01352
    Location:2867
    KRAB; KRAB box

RNA

  1. XR_005502578.2 RNA Sequence