U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

trpc3 transient receptor potential cation channel, subfamily C, member 3 [ Danio rerio (zebrafish) ]

Gene ID: 101887082, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
trpc3provided by ZNC
Official Full Name
transient receptor potential cation channel, subfamily C, member 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-140129-1
See related
AllianceGenome:ZFIN:ZDB-GENE-140129-1
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable inositol 1,4,5 trisphosphate binding activity and store-operated calcium channel activity. Predicted to be involved in calcium ion transmembrane transport; regulation of cytosolic calcium ion concentration; and single fertilization. Predicted to act upstream of or within monoatomic ion transport and transmembrane transport. Predicted to be located in membrane. Predicted to be part of cation channel complex. Predicted to be active in plasma membrane. Is expressed in nervous system. Human ortholog(s) of this gene implicated in cerebellar ataxia type 41. Orthologous to human TRPC3 (transient receptor potential cation channel subfamily C member 3). [provided by Alliance of Genome Resources, Dec 2024]
Annotation information
Annotation category: suggests misassembly
Annotation category: partial on reference assembly
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See trpc3 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (3411621..3465892)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (3304305..3358586)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110440216 Neighboring gene im:7150988 Neighboring gene glutathione S-transferase pi 1.1 Neighboring gene glutathione S-transferase pi 1.2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Phylogeny and expression of canonical transient receptor potential (TRPC) genes in developing zebrafish. Von Niederhäusern V, et al. Dev Dyn, 2013 Dec. PMID 24038627
  2. Red LED light treatment promotes cognitive learning through up-regulation of trpm4 in zebrafish. You MS, et al. J Photochem Photobiol B, 2020 Dec. PMID 33186875
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium channel activity IEA
Inferred from Electronic Annotation
more info
  
enables monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
short transient receptor potential channel 3
Names
short transient receptor potential channel 3-like

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001289884.2 → NP_001276813.2  short transient receptor potential channel 3

    Status: VALIDATED

    Source sequence(s)
    CABZ01073823, CABZ01073825, FP102983, KF446630
    UniProtKB/TrEMBL
    A0A8M1P0G4, U3N8Z0
    Conserved Domains (4) summary
    cd00204
    Location:101 → 233
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    TIGR00870
    Location:78 → 869
    trp; transient-receptor-potential calcium channel protein
    pfam08344
    Location:247 → 306
    TRP_2; Transient receptor ion channel II
    sd00045
    Location:128 → 159
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    3411621..3465892
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.