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fgfbp1b fibroblast growth factor binding protein 1b [ Danio rerio (zebrafish) ]

Gene ID: 101886353, updated on 4-Jan-2025

Summary

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Official Symbol
fgfbp1bprovided by ZNC
Official Full Name
fibroblast growth factor binding protein 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-081106-1
See related
Ensembl:ENSDARG00000091660 AllianceGenome:ZFIN:ZDB-GENE-081106-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fc20g06
Summary
Predicted to enable growth factor binding activity. Predicted to be involved in cell-cell signaling. Predicted to be located in extracellular region. Is expressed in brain; head; and otic vesicle. Orthologous to human FGFBP1 (fibroblast growth factor binding protein 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See fgfbp1b in Genome Data Viewer
Location:
chromosome: 1
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (22676698..22678468, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (21985958..21987829, complement)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) Neighboring gene annexin A5b Neighboring gene fibroblast growth factor binding protein 2b Neighboring gene zinc finger, MYND-type containing 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Temporal and spatial expression of fgfbp genes in zebrafish. Li Y, et al. Gene, 2018 Jun 15. PMID 29551495
  2. A zebrafish model of foxe3 deficiency demonstrates lens and eye defects with dysregulation of key genes involved in cataract formation in humans. Krall M, et al. Hum Genet, 2018 Apr. PMID 29713869, Free PMC Article
  3. Gene Characterization of Nocturnin Paralogues in Goldfish: Full Coding Sequences, Structure, Phylogeny and Tissue Expression. Madera D, et al. Int J Mol Sci, 2023 Dec 19. PMID 38203224, Free PMC Article
  4. Genetic control of cellular morphogenesis in Müller glia. Charlton-Perkins M, et al. Glia, 2019 Jul. PMID 30924555, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables growth factor binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables growth factor binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell-cell signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
fibroblast growth factor-binding protein 1
Names
fgfbp1
fibroblast growth factor-binding protein 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    22676698..22678468 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021476334.2 → XP_021332009.1  fibroblast growth factor-binding protein 1

    UniProtKB/TrEMBL
    A0A8M9Q0I5, E7FEC7
    Related
    ENSDARP00000105647.1, ENSDART00000128918.3
    Conserved Domains (1) summary
    pfam06473
    Location:10 → 203
    FGF-BP1; FGF binding protein 1 (FGF-BP1)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394480.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    10234..12004 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021471190.2 → XP_021326865.1  fibroblast growth factor-binding protein 1

    UniProtKB/TrEMBL
    A0A8M9Q0I5, E7FEC7
    Conserved Domains (1) summary
    pfam06473
    Location:10 → 203
    FGF-BP1; FGF binding protein 1 (FGF-BP1)

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395214.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    10234..12004 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005170938.5 → XP_005170995.1  fibroblast growth factor-binding protein 1

    UniProtKB/TrEMBL
    A0A8M9Q0I5, E7FEC7
    Conserved Domains (1) summary
    pfam06473
    Location:10 → 203
    FGF-BP1; FGF binding protein 1 (FGF-BP1)
Nucleotide Protein Strain
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