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colq collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase [ Danio rerio (zebrafish) ]

Gene ID: 101886065, updated on 9-Dec-2024

Summary

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Official Symbol
colqprovided by ZNC
Official Full Name
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesteraseprovided by ZNC
Primary source
ZFIN:ZDB-GENE-110411-119
See related
Ensembl:ENSDARG00000019692 AllianceGenome:ZFIN:ZDB-GENE-110411-119
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkeyp-86h10.5
Summary
Predicted to enable heparin binding activity. Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in extracellular matrix organization. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 5. Orthologous to human COLQ (collagen like tail subunit of asymmetric acetylcholinesterase). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See colq in Genome Data Viewer
Location:
chromosome: 16
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (20198897..20240307)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (20393026..20430347)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene chromosome 16 C2orf66 homolog Neighboring gene 2-hydroxyacyl-CoA lyase 1 Neighboring gene pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 Neighboring gene FKBP prolyl isomerase 14

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
acetylcholinesterase collagenic tail peptide

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    20198897..20240307
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009292268.4 → XP_009290543.1  acetylcholinesterase collagenic tail peptide isoform X1

    UniProtKB/TrEMBL
    A0A8M3ATD0
    Conserved Domains (3) summary
    pfam01391
    Location:143 → 200
    Collagen; Collagen triple helix repeat (20 copies)
    TIGR02232
    Location:385 → 409
    myxo_disulf_rpt; Myxococcus cysteine-rich repeat
    pfam13948
    Location:384 → 413
    DUF4215; Domain of unknown function (DUF4215)

  2. XM_005157972.5 → XP_005158029.1  acetylcholinesterase collagenic tail peptide isoform X2

    UniProtKB/TrEMBL
    A0A8M2B499, F1Q7Y1
    Related
    ENSDARP00000019894.8, ENSDART00000006037.9
    Conserved Domains (3) summary
    pfam01391
    Location:137 → 195
    Collagen; Collagen triple helix repeat (20 copies)
    TIGR02232
    Location:373 → 397
    myxo_disulf_rpt; Myxococcus cysteine-rich repeat
    pfam13948
    Location:372 → 401
    DUF4215; Domain of unknown function (DUF4215)
Nucleotide Protein
Heading Accession and Version

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