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CG42694 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 10178792, updated on 9-Dec-2024

Summary

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Official Symbol
CG42694provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0261584
Locus tag
Dmel_CG42694
See related
AllianceGenome:FB:FBgn0261584
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG42694; SPH247
Summary
Predicted to be involved in innate immune response. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG42694 in Genome Data Viewer
Location:
59B7-59B7; 2-101 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22941877..22945147)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18829400..18832670)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene CCHC-type zinc finger nucleic acid binding protein Neighboring gene uncharacterized protein Neighboring gene Gustatory receptor-like Holozoa Neighboring gene mir-9376 stem loop Neighboring gene long non-coding RNA:CR32835

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The tobacco phosphatidylethanolamine-binding protein NtFT4 increases the lifespan of Drosophila melanogaster by interacting with the proteostasis network. Känel P, et al. Aging (Albany NY), 2022 Apr 8. PMID 35396341, Free PMC Article
  2. Building a platform for predicting functions of serine protease-related proteins in Drosophila melanogaster and other insects. Cao X, et al. Insect Biochem Mol Biol, 2018 Dec. PMID 30367934, Free PMC Article
  3. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article
  4. Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species. Sanfilippo P, et al. Genome Biol, 2017 Nov 30. PMID 29191225, Free PMC Article
  5. Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster. Liu X, et al. RNA, 2017 Dec. PMID 28851752, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
NOT enables peptidase activity IKR
Inferred from Key Residues
more info
  
NOT enables serine-type endopeptidase activity IKR
Inferred from Key Residues
more info
 PubMed 
Process Evidence Code Pubs
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG42694-PA
CG42694-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    22941877..22945147
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001274218.2 → NP_001261147.1  uncharacterized protein Dmel_CG42694, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261147.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4JD89
    Conserved Domains (2) summary
    smart00020
    Location:46 → 253
    Tryp_SPc; Trypsin-like serine protease
    cl21584
    Location:46 → 256
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

  2. NM_001202065.2 → NP_001188994.1  uncharacterized protein Dmel_CG42694, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001188994.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4JD89
    Conserved Domains (2) summary
    smart00020
    Location:46 → 253
    Tryp_SPc; Trypsin-like serine protease
    cl21584
    Location:46 → 256
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4JD89 A0A0B4JD89

Gene LinkOut

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