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RXRA retinoid X receptor alpha [ Orcinus orca (killer whale) ]

Gene ID: 101270600, updated on 8-Mar-2024

Summary

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Gene symbol
RXRA
Gene description
retinoid X receptor alpha
See related
EnsemblRapid:ENSOORG00010018309
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See RXRA in Genome Data Viewer
Location:
chromosome: 6
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 6 NC_064564.1 (118074464..118171621, complement)

Chromosome 6 - NC_064564.1Genomic Context describing neighboring genes Neighboring gene ficolin-1-like Neighboring gene collagen type V alpha 1 chain Neighboring gene uncharacterized LOC117198475 Neighboring gene U6atac minor spliceosomal RNA Neighboring gene WD repeat domain 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064564.1 Chromosome 6 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. PCB-associated changes in mRNA expression in killer whales (Orcinus orca) from the NE Pacific Ocean. Buckman AH, et al. Environ Sci Technol, 2011 Dec 1. PMID 21985468
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear steroid receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables retinoic acid-responsive element binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in anatomical structure development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to retinoic acid IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in retinoic acid receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of RNA polymerase II transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
retinoic acid receptor RXR-alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064564.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    118074464..118171621 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033415158.2 → XP_033271049.1  retinoic acid receptor RXR-alpha isoform X4

    Conserved Domains (3) summary
    cd06943
    Location:262 → 473
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:138 → 209
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    pfam11825
    Location:18 → 131
    Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

  2. XM_049711459.1 → XP_049567416.1  retinoic acid receptor RXR-alpha isoform X5

    Related
    ENSOORP00010024039.1, ENSOORT00010027368.1

  3. XM_049711458.1 → XP_049567415.1  retinoic acid receptor RXR-alpha isoform X2

  4. XM_033415161.2 → XP_033271052.1  retinoic acid receptor RXR-alpha isoform X2

    Conserved Domains (3) summary
    cd06943
    Location:234 → 445
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:110 → 181
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    pfam11825
    Location:1 → 103
    Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

  5. XM_033415160.2 → XP_033271051.1  retinoic acid receptor RXR-alpha isoform X2

    Conserved Domains (3) summary
    cd06943
    Location:234 → 445
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:110 → 181
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    pfam11825
    Location:1 → 103
    Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

  6. XM_033415162.2 → XP_033271053.1  retinoic acid receptor RXR-alpha isoform X3

    Conserved Domains (3) summary
    cd06943
    Location:160 → 371
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:36 → 107
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    pfam11825
    Location:1 → 29
    Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

  7. XM_049711457.1 → XP_049567414.1  retinoic acid receptor RXR-alpha isoform X1

Nucleotide Protein
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