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SYNGAP1 synaptic Ras GTPase activating protein 1 [ Papio anubis (olive baboon) ]

Gene ID: 100999790, updated on 8-Mar-2024

Summary

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Gene symbol
SYNGAP1
Gene description
synaptic Ras GTPase activating protein 1
See related
Ensembl:ENSPANG00000014561
Gene type
protein coding
RefSeq status
MODEL
Organism
Papio anubis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Papio
Orthologs
human mouse all
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Genomic context

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See SYNGAP1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
25
Annotation release Status Assembly Chr Location
104 current Panubis1.0 (GCF_008728515.1) 6 NC_044981.1 (31761385..31796811)
103 previous assembly Panu_3.0 (GCF_000264685.3) 4 NC_018155.2 (32783836..32817396)

Chromosome 6 - NC_044981.1Genomic Context describing neighboring genes Neighboring gene kinesin family member C1 Neighboring gene PHD finger protein 1 Neighboring gene cutA divalent cation tolerance homolog Neighboring gene zinc finger and BTB domain containing 9 Neighboring gene BCL2 antagonist/killer 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in negative regulation of Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras/Rap GTPase-activating protein SynGAP

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Papio anubis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Panubis1.0 Primary Assembly

Genomic

  1. NC_044981.1 Reference Panubis1.0 Primary Assembly

    Range
    31761385..31796811
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031667037.1 → XP_031522897.1  ras/Rap GTPase-activating protein SynGAP isoform X4

    UniProtKB/TrEMBL
    A0A096NHI9
    Conserved Domains (4) summary
    cd04013
    Location:224 → 386
    C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
    cd05136
    Location:377 → 700
    RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
    cd13375
    Location:94 → 285
    PH_SynGAP; Synaptic Ras-GTPase activating protein Pleckstrin homology (PH) domain
    pfam12004
    Location:690 → 1267
    DUF3498; Domain of unknown function (DUF3498)

  2. XM_031667038.1 → XP_031522898.1  ras/Rap GTPase-activating protein SynGAP isoform X4

    UniProtKB/TrEMBL
    A0A096NHI9
    Conserved Domains (4) summary
    cd04013
    Location:224 → 386
    C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
    cd05136
    Location:377 → 700
    RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
    cd13375
    Location:94 → 285
    PH_SynGAP; Synaptic Ras-GTPase activating protein Pleckstrin homology (PH) domain
    pfam12004
    Location:690 → 1267
    DUF3498; Domain of unknown function (DUF3498)

  3. XM_031667033.1 → XP_031522893.1  ras/Rap GTPase-activating protein SynGAP isoform X2

    UniProtKB/TrEMBL
    A0A096NHI9, A0A2I3MB45
    Related
    ENSPANP00000032951.2, ENSPANT00000038574.2
    Conserved Domains (4) summary
    cd04013
    Location:252 → 414
    C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
    cd05136
    Location:405 → 728
    RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
    cd13375
    Location:122 → 313
    PH_SynGAP; Synaptic Ras-GTPase activating protein Pleckstrin homology (PH) domain
    pfam12004
    Location:718 → 1310
    DUF3498; Domain of unknown function (DUF3498)

  4. XM_031667039.1 → XP_031522899.1  ras/Rap GTPase-activating protein SynGAP isoform X5

    UniProtKB/TrEMBL
    A0A096NHI9, A0A2I3MTC4
    Related
    ENSPANP00000038994.2, ENSPANT00000056678.2
    Conserved Domains (4) summary
    cd04013
    Location:252 → 414
    C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
    cd05136
    Location:405 → 728
    RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
    cd13375
    Location:122 → 313
    PH_SynGAP; Synaptic Ras-GTPase activating protein Pleckstrin homology (PH) domain
    pfam12004
    Location:718 → 1295
    DUF3498; Domain of unknown function (DUF3498)

  5. XM_031667041.1 → XP_031522901.1  ras/Rap GTPase-activating protein SynGAP isoform X7

    UniProtKB/TrEMBL
    A0A096NHI9
    Conserved Domains (4) summary
    cd04013
    Location:252 → 414
    C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
    cd05136
    Location:405 → 728
    RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
    cd13375
    Location:122 → 313
    PH_SynGAP; Synaptic Ras-GTPase activating protein Pleckstrin homology (PH) domain
    pfam12004
    Location:718 → 1262
    DUF3498; Domain of unknown function (DUF3498)

  6. XM_031667031.1 → XP_031522891.1  ras/Rap GTPase-activating protein SynGAP isoform X1

    UniProtKB/TrEMBL
    A0A096NHI9, A0A2I3M6K6
    Related
    ENSPANP00000031357.2, ENSPANT00000056014.2
    Conserved Domains (4) summary
    cd04013
    Location:252 → 414
    C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
    cd05136
    Location:405 → 728
    RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
    cd13375
    Location:122 → 313
    PH_SynGAP; Synaptic Ras-GTPase activating protein Pleckstrin homology (PH) domain
    pfam12004
    Location:718 → 1295
    DUF3498; Domain of unknown function (DUF3498)

  7. XM_031667034.1 → XP_031522894.1  ras/Rap GTPase-activating protein SynGAP isoform X3

    UniProtKB/TrEMBL
    A0A096NHI9
    Conserved Domains (4) summary
    cd04013
    Location:252 → 414
    C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
    cd05136
    Location:405 → 728
    RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
    cd13375
    Location:122 → 313
    PH_SynGAP; Synaptic Ras-GTPase activating protein Pleckstrin homology (PH) domain
    pfam12004
    Location:718 → 1279
    DUF3498; Domain of unknown function (DUF3498)

  8. XM_031667036.1 → XP_031522896.1  ras/Rap GTPase-activating protein SynGAP isoform X4

    UniProtKB/TrEMBL
    A0A096NHI9
    Conserved Domains (4) summary
    cd04013
    Location:224 → 386
    C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
    cd05136
    Location:377 → 700
    RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
    cd13375
    Location:94 → 285
    PH_SynGAP; Synaptic Ras-GTPase activating protein Pleckstrin homology (PH) domain
    pfam12004
    Location:690 → 1267
    DUF3498; Domain of unknown function (DUF3498)

  9. XM_031667035.1 → XP_031522895.1  ras/Rap GTPase-activating protein SynGAP isoform X4

    UniProtKB/TrEMBL
    A0A096NHI9
    Conserved Domains (4) summary
    cd04013
    Location:224 → 386
    C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
    cd05136
    Location:377 → 700
    RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
    cd13375
    Location:94 → 285
    PH_SynGAP; Synaptic Ras-GTPase activating protein Pleckstrin homology (PH) domain
    pfam12004
    Location:690 → 1267
    DUF3498; Domain of unknown function (DUF3498)

  10. XM_031667043.1 → XP_031522903.1  ras/Rap GTPase-activating protein SynGAP isoform X9

    UniProtKB/TrEMBL
    A0A096NHI9
    Conserved Domains (4) summary
    cd04013
    Location:135 → 297
    C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
    cd05136
    Location:288 → 611
    RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
    cd13375
    Location:5 → 196
    PH_SynGAP; Synaptic Ras-GTPase activating protein Pleckstrin homology (PH) domain
    pfam12004
    Location:601 → 1178
    DUF3498; Domain of unknown function (DUF3498)

  11. XM_031667044.1 → XP_031522904.1  ras/Rap GTPase-activating protein SynGAP isoform X9

    UniProtKB/TrEMBL
    A0A096NHI9
    Conserved Domains (4) summary
    cd04013
    Location:135 → 297
    C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
    cd05136
    Location:288 → 611
    RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
    cd13375
    Location:5 → 196
    PH_SynGAP; Synaptic Ras-GTPase activating protein Pleckstrin homology (PH) domain
    pfam12004
    Location:601 → 1178
    DUF3498; Domain of unknown function (DUF3498)

  12. XM_031667042.1 → XP_031522902.1  ras/Rap GTPase-activating protein SynGAP isoform X8

    UniProtKB/TrEMBL
    A0A096NHI9
    Related
    ENSPANP00000012437.3, ENSPANT00000012395.3
    Conserved Domains (4) summary
    cd04013
    Location:166 → 328
    C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
    cd05136
    Location:319 → 642
    RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
    cd13375
    Location:36 → 227
    PH_SynGAP; Synaptic Ras-GTPase activating protein Pleckstrin homology (PH) domain
    pfam12004
    Location:632 → 1209
    DUF3498; Domain of unknown function (DUF3498)

  13. XM_031667040.1 → XP_031522900.1  ras/Rap GTPase-activating protein SynGAP isoform X6

    UniProtKB/TrEMBL
    A0A096NHI9
    Conserved Domains (4) summary
    cd04013
    Location:193 → 355
    C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
    cd05136
    Location:346 → 669
    RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
    cd13375
    Location:63 → 254
    PH_SynGAP; Synaptic Ras-GTPase activating protein Pleckstrin homology (PH) domain
    pfam12004
    Location:659 → 1236
    DUF3498; Domain of unknown function (DUF3498)

RNA

  1. XR_004184264.1 RNA Sequence

    Related
    ENSPANT00000082022.1

  2. XR_004184261.1 RNA Sequence

  3. XR_004184263.1 RNA Sequence

  4. XR_004184262.1 RNA Sequence

Nucleotide Protein
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