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Casp3 caspase 3 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100689061, updated on 14-Nov-2024

Summary

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Gene symbol
Casp3
Gene description
caspase 3
See related
Ensembl:ENSCGRG00015021086
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Also known as
caspase-3
Orthologs
human mouse all
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Genomic context

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See Casp3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613593.1 (3054603..3073650, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 1 Unlocalized Scaffold NW_023276807.1 (40011099..40019323, complement)

NW_003613593.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103162237 Neighboring gene uncharacterized LOC103162238 Neighboring gene primase and DNA directed polymerase Neighboring gene centromere protein U Neighboring gene uncharacterized protein C3orf38 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Okadaic acid induces DNA fragmentation via caspase-3-dependent and caspase-3-independent pathways in Chinese hamster ovary (CHO)-K1 cells. Kitazumi I, et al. FEBS J, 2010 Jan. PMID 19968860
  2. Inhibition of sodium butyrate-induced apoptosis in recombinant Chinese hamster ovary cells by constitutively expressing antisense RNA of caspase-3. Kim NS, et al. Biotechnol Bioeng, 2002 Apr 20. PMID 11870612
  3. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in erythrocyte differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in keratinocyte differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
caspase-3
Names
caspase 3, apoptosis-related cysteine peptidase
NP_001230975.1
XP_007639410.1
XP_007639414.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001244046.1 → NP_001230975.1  caspase-3

    See identical proteins and their annotated locations for NP_001230975.1

    Status: PROVISIONAL

    Source sequence(s)
    FJ940732
    UniProtKB/TrEMBL
    A0A8C2LMQ6, C4PFX6
    Related
    ENSCGRP00015027820.2, ENSCGRT00015034081.2
    Conserved Domains (1) summary
    smart00115
    Location:37 → 276
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues

RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613593.1 Reference CriGri_1.0 Primary Assembly

    Range
    3054603..3073650 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007641224.4 → XP_007639414.1  caspase-3 isoform X2

    See identical proteins and their annotated locations for XP_007639414.1

    UniProtKB/TrEMBL
    A0A8C2LMQ6, C4PFX6
    Conserved Domains (1) summary
    smart00115
    Location:37 → 276
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues

  2. XM_007641220.4 → XP_007639410.1  caspase-3 isoform X1

    See identical proteins and their annotated locations for XP_007639410.1

    UniProtKB/TrEMBL
    A0A8C2LMQ6
    Conserved Domains (1) summary
    smart00115
    Location:57 → 296
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues

Alternate CriGri-PICRH-1.0

Genomic

  1. NW_023276807.1 Alternate CriGri-PICRH-1.0

    Range
    40011099..40019323 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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