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Mir5046 microRNA 5046 [ Mus musculus (house mouse) ]

Gene ID: 100628576, updated on 17-Aug-2024

Summary

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Official Symbol
Mir5046provided by MGI
Official Full Name
microRNA 5046provided by MGI
Primary source
MGI:MGI:4950413
See related
Ensembl:ENSMUSG00000104884 miRBase:MI0017931; AllianceGenome:MGI:4950413
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mu-mir-5046; mmu-mir-5046
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

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See Mir5046 in Genome Data Viewer
Location:
19 A; 19 5.08 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (6807254..6807312, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (6829886..6829944, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32245 Neighboring gene high mobility group box 1, pseudogene 4 Neighboring gene STARR-seq mESC enhancer starr_45439 Neighboring gene STARR-seq mESC enhancer starr_45441 Neighboring gene ribosomal protein S6 kinase, polypeptide 4 Neighboring gene coiled-coil domain containing 88B Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:6946569-6946770 Neighboring gene predicted gene, 54051

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mesenchymal miR-21 regulates branching morphogenesis in murine submandibular gland in vitro. Hayashi T, et al. Dev Biol, 2011 Apr 15. PMID 21295561
  2. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Other Names

  • microRNA mir-5046

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_039555.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    FO082334
    Related
    ENSMUST00000199140.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    6807254..6807312 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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