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GRIN2B glutamate ionotropic receptor NMDA type subunit 2B [ Sus scrofa (pig) ]

Gene ID: 100626022, updated on 17-Aug-2024

Summary

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Official Symbol
GRIN2Bprovided by VGNC
Official Full Name
glutamate ionotropic receptor NMDA type subunit 2Bprovided by VGNC
Primary source
VGNC:VGNC:88684
See related
Ensembl:ENSSSCG00000000614
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Low expression observed in reference dataset See more
Orthologs
human mouse all
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Genomic context

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See GRIN2B in Genome Data Viewer
Location:
chromosome: 5
Exon count:
19
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 5 NC_010447.5 (58477862..58948735)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 5 NC_010447.4 (61874217..62275930)

Chromosome 5 - NC_010447.5Genomic Context describing neighboring genes Neighboring gene phospholipase B domain containing 1 Neighboring gene activating transcription factor 7 interacting protein Neighboring gene ferritin light chain-like Neighboring gene epithelial membrane protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NMDA glutamate receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in excitatory postsynaptic potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in long-term synaptic potentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synaptic transmission, glutamatergic IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NMDA selective glutamate receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
glutamate receptor ionotropic, NMDA 2B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010447.5 Reference Sscrofa11.1 Primary Assembly

    Range
    58477862..58948735
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021092316.1 → XP_020947975.1  glutamate receptor ionotropic, NMDA 2B

    UniProtKB/TrEMBL
    A0A4X1V2X7, A0A8D2CHB5, F1SQ84
    Conserved Domains (3) summary
    cd06378
    Location:33 → 393
    PBP1_iGluR_NMDA_NR2; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
    cd13718
    Location:403 → 803
    PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    pfam10565
    Location:840 → 1484
    NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

  2. XM_021092318.1 → XP_020947977.1  glutamate receptor ionotropic, NMDA 2B

    UniProtKB/TrEMBL
    A0A4X1V2X7, A0A8D2CHB5, F1SQ84
    Conserved Domains (3) summary
    cd06378
    Location:33 → 393
    PBP1_iGluR_NMDA_NR2; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
    cd13718
    Location:403 → 803
    PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    pfam10565
    Location:840 → 1484
    NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

  3. XM_021092315.1 → XP_020947974.1  glutamate receptor ionotropic, NMDA 2B

    UniProtKB/TrEMBL
    A0A4X1V2X7, A0A8D2CHB5, F1SQ84
    Conserved Domains (3) summary
    cd06378
    Location:33 → 393
    PBP1_iGluR_NMDA_NR2; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
    cd13718
    Location:403 → 803
    PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    pfam10565
    Location:840 → 1484
    NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

  4. XM_021092317.1 → XP_020947976.1  glutamate receptor ionotropic, NMDA 2B

    UniProtKB/TrEMBL
    A0A4X1V2X7, A0A8D2CHB5, F1SQ84
    Conserved Domains (3) summary
    cd06378
    Location:33 → 393
    PBP1_iGluR_NMDA_NR2; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
    cd13718
    Location:403 → 803
    PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    pfam10565
    Location:840 → 1484
    NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

  5. XM_021092314.1 → XP_020947973.1  glutamate receptor ionotropic, NMDA 2B

    UniProtKB/TrEMBL
    A0A4X1V2X7, A0A8D2CHB5, F1SQ84
    Related
    ENSSSCP00000032116.1, ENSSSCT00000061900.3
    Conserved Domains (3) summary
    cd06378
    Location:33 → 393
    PBP1_iGluR_NMDA_NR2; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
    cd13718
    Location:403 → 803
    PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    pfam10565
    Location:840 → 1484
    NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

  6. XM_021092319.1 → XP_020947978.1  glutamate receptor ionotropic, NMDA 2B

    UniProtKB/TrEMBL
    A0A4X1V2X7, A0A8D2CHB5, F1SQ84
    Conserved Domains (3) summary
    cd06378
    Location:33 → 393
    PBP1_iGluR_NMDA_NR2; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
    cd13718
    Location:403 → 803
    PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    pfam10565
    Location:840 → 1484
    NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

  7. XM_021092320.1 → XP_020947979.1  glutamate receptor ionotropic, NMDA 2B

    UniProtKB/TrEMBL
    A0A4X1V2X7, A0A8D2CHB5, F1SQ84
    Conserved Domains (3) summary
    cd06378
    Location:33 → 393
    PBP1_iGluR_NMDA_NR2; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
    cd13718
    Location:403 → 803
    PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    pfam10565
    Location:840 → 1484
    NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus
Nucleotide Protein
Heading Accession and Version

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