U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ttyh1 tweety family member 1 [ Danio rerio (zebrafish) ]

Gene ID: 100537642, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
ttyh1provided by ZNC
Official Full Name
tweety family member 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-100922-257
See related
Ensembl:ENSDARG00000076804 AllianceGenome:ZFIN:ZDB-GENE-100922-257
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkeyp-68a7.2
Summary
Predicted to enable intracellularly calcium-gated chloride channel activity and volume-sensitive chloride channel activity. Predicted to act upstream of or within chloride transport and monoatomic ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of chloride channel complex. Predicted to be active in plasma membrane and smooth endoplasmic reticulum membrane. Orthologous to human TTYH1 (tweety family member 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ttyh1 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (13713646..13804499, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (13823526..13914426, complement)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2S Neighboring gene Josephin domain containing 2 Neighboring gene leukocyte receptor cluster (LRC) member 9 Neighboring gene folliculin

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables chloride channel activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within chloride transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of chloride channel complex IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
protein tweety homolog 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    13713646..13804499 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021466873.2 → XP_021322548.1  protein tweety homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M9P885, F1QZT2
    Conserved Domains (1) summary
    cl12141
    Location:9 → 480
    Tweety_N; N-terminal domain of the protein encoded by the Drosophila tweety gene and related proteins, a family of chloride ion channels

  2. XM_021466872.2 → XP_021322547.1  protein tweety homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M9P885, F1QZT2
    Conserved Domains (1) summary
    cl12141
    Location:9 → 480
    Tweety_N; N-terminal domain of the protein encoded by the Drosophila tweety gene and related proteins, a family of chloride ion channels

  3. XM_021466874.2 → XP_021322549.1  protein tweety homolog 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PDI6, F1QZT2
    Related
    ENSDARP00000117502.2, ENSDART00000138540.3
    Conserved Domains (1) summary
    cl12141
    Location:9 → 480
    Tweety_N; N-terminal domain of the protein encoded by the Drosophila tweety gene and related proteins, a family of chloride ion channels

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394957.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    263824..326005 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021472973.2 → XP_021328648.1  protein tweety homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PNN5, F1QZT2
    Conserved Domains (1) summary
    cl12141
    Location:9 → 480
    Tweety_N; N-terminal domain of the protein encoded by the Drosophila tweety gene and related proteins, a family of chloride ion channels

  2. XM_009292147.4 → XP_009290422.2  protein tweety homolog 1 isoform X4

    UniProtKB/TrEMBL
    A0A8M3AIZ3, F1QZT2
    Conserved Domains (1) summary
    cl12141
    Location:9 → 480
    Tweety_N; N-terminal domain of the protein encoded by the Drosophila tweety gene and related proteins, a family of chloride ion channels

  3. XM_009292145.4 → XP_009290420.2  protein tweety homolog 1 isoform X3

    UniProtKB/TrEMBL
    A0A8M3AHW7, F1QZT2
    Conserved Domains (1) summary
    cl12141
    Location:9 → 480
    Tweety_N; N-terminal domain of the protein encoded by the Drosophila tweety gene and related proteins, a family of chloride ion channels

  4. XM_009292146.4 → XP_009290421.2  protein tweety homolog 1 isoform X3

    UniProtKB/TrEMBL
    A0A8M3AHW7, F1QZT2
    Conserved Domains (1) summary
    cl12141
    Location:9 → 480
    Tweety_N; N-terminal domain of the protein encoded by the Drosophila tweety gene and related proteins, a family of chloride ion channels

  5. XM_003200152.6 → XP_003200200.3  protein tweety homolog 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M1RT32, F1QZT2
    Conserved Domains (1) summary
    cl12141
    Location:9 → 480
    Tweety_N; N-terminal domain of the protein encoded by the Drosophila tweety gene and related proteins, a family of chloride ion channels
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.