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baiap2b BAR/IMD domain containing adaptor protein 2b [ Danio rerio (zebrafish) ]

Gene ID: 100537012, updated on 9-Dec-2024

Summary

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Official Symbol
baiap2bprovided by ZNC
Official Full Name
BAR/IMD domain containing adaptor protein 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-100812-7
See related
Ensembl:ENSDARG00000103333 AllianceGenome:ZFIN:ZDB-GENE-100812-7
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable cytoskeletal anchor activity. Predicted to be involved in actin crosslink formation; actin filament bundle assembly; and positive regulation of actin filament polymerization. Predicted to act upstream of or within plasma membrane organization and regulation of actin cytoskeleton organization. Predicted to be located in several cellular components, including cytoskeleton; filopodium; and ruffle. Predicted to be active in cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome; attention deficit hyperactivity disorder; and autism spectrum disorder. Orthologous to human BAIAP2 (BAR/IMD domain containing adaptor protein 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See baiap2b in Genome Data Viewer
Location:
chromosome: 12
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (35606346..35692562)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (35911928..36004511)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene SEC24 homolog C, COPII coat complex component Neighboring gene charged multivesicular body protein 6b Neighboring gene microRNA 338-1 Neighboring gene apoptosis-associated tyrosine kinase b Neighboring gene ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cytoskeletal anchor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within plasma membrane organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in filopodium IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in ruffle IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
BAR/IMD domain-containing adapter protein 2
Names
BAI1-associated protein 2b

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    35606346..35692562
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068224811.1 → XP_068080912.1  BAR/IMD domain-containing adapter protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8M3B4T7

  2. XM_068224808.1 → XP_068080909.1  BAR/IMD domain-containing adapter protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8M3AYK1

  3. XM_068224810.1 → XP_068080911.1  BAR/IMD domain-containing adapter protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8M3B4T7

  4. XM_068224807.1 → XP_068080908.1  BAR/IMD domain-containing adapter protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M3BEB0

  5. XM_068224809.1 → XP_068080910.1  BAR/IMD domain-containing adapter protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8M1RME1

  6. XM_068224813.1 → XP_068080914.1  BAR/IMD domain-containing adapter protein 2 isoform X6

    UniProtKB/TrEMBL
    A0A8M3BEB0

  7. XM_068224812.1 → XP_068080913.1  BAR/IMD domain-containing adapter protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A8M3BEB0

  8. XM_068224814.1 → XP_068080915.1  BAR/IMD domain-containing adapter protein 2 isoform X7

    UniProtKB/TrEMBL
    A0A8M9PSD4
    Related
    ENSDARP00000138148.2, ENSDART00000169889.2

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394858.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    10718..73875
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068218693.1 → XP_068074794.1  BAR/IMD domain-containing adapter protein 2 isoform X10

    UniProtKB/TrEMBL
    A0A8M9PSD9

  2. XM_068218690.1 → XP_068074791.1  BAR/IMD domain-containing adapter protein 2 isoform X8

    UniProtKB/TrEMBL
    A0A8M9PMK4

  3. XM_068218692.1 → XP_068074793.1  BAR/IMD domain-containing adapter protein 2 isoform X10

    UniProtKB/TrEMBL
    A0A8M9PSD9

  4. XM_068218691.1 → XP_068074792.1  BAR/IMD domain-containing adapter protein 2 isoform X9

    UniProtKB/TrEMBL
    A0A8M9Q4S2

  5. XM_068218695.1 → XP_068074796.1  BAR/IMD domain-containing adapter protein 2 isoform X12

    UniProtKB/TrEMBL
    A0A8M9PSD4

  6. XM_068218697.1 → XP_068074798.1  BAR/IMD domain-containing adapter protein 2 isoform X13

    UniProtKB/TrEMBL
    A0A8M9PSD4

  7. XM_068218694.1 → XP_068074795.1  BAR/IMD domain-containing adapter protein 2 isoform X11

    UniProtKB/TrEMBL
    A0A8M9PSD4

  8. XM_068218696.1 → XP_068074797.1  BAR/IMD domain-containing adapter protein 2 isoform X7

    UniProtKB/TrEMBL
    A0A8M9PSD4

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395304.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    10718..74100
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068219314.1 → XP_068075415.1  BAR/IMD domain-containing adapter protein 2 isoform X20

    UniProtKB/TrEMBL
    A0A8M9PTP3

  2. XM_068219311.1 → XP_068075412.1  BAR/IMD domain-containing adapter protein 2 isoform X18

    UniProtKB/TrEMBL
    A0A8M9PSD9

  3. XM_068219313.1 → XP_068075414.1  BAR/IMD domain-containing adapter protein 2 isoform X19

    UniProtKB/TrEMBL
    A0A8M9PSD9

  4. XM_068219309.1 → XP_068075410.1  BAR/IMD domain-containing adapter protein 2 isoform X15

    UniProtKB/TrEMBL
    A0A8M9PMK4

  5. XM_068219312.1 → XP_068075413.1  BAR/IMD domain-containing adapter protein 2 isoform X19

    UniProtKB/TrEMBL
    A0A8M9PSD9

  6. XM_068219308.1 → XP_068075409.1  BAR/IMD domain-containing adapter protein 2 isoform X14

    UniProtKB/TrEMBL
    A0A8M9PSD4

  7. XM_068219310.1 → XP_068075411.1  BAR/IMD domain-containing adapter protein 2 isoform X17

    UniProtKB/TrEMBL
    A0A8M9Q4S2

  8. XM_068219316.1 → XP_068075417.1  BAR/IMD domain-containing adapter protein 2 isoform X22

    UniProtKB/TrEMBL
    A0A8M9Q4S0

  9. XM_021474262.2 → XP_021329937.1  BAR/IMD domain-containing adapter protein 2 isoform X16

    UniProtKB/TrEMBL
    A0A8M9PFG9, A0A8M9PTN8
    Conserved Domains (2) summary
    cd11915
    Location:332 → 390
    SH3_Irsp53; Src Homology 3 domain of Insulin Receptor tyrosine kinase Substrate p53
    cl12013
    Location:1 → 187
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  10. XM_068219315.1 → XP_068075416.1  BAR/IMD domain-containing adapter protein 2 isoform X21

    UniProtKB/TrEMBL
    A0A8M9PTN8
Nucleotide Protein Strain
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