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mrasa muscle RAS oncogene homolog a [ Danio rerio (zebrafish) ]

Gene ID: 100536317, updated on 9-Dec-2024

Summary

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Official Symbol
mrasaprovided by ZNC
Official Full Name
muscle RAS oncogene homolog aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-110411-67
See related
Ensembl:ENSDARG00000075285 AllianceGenome:ZFIN:ZDB-GENE-110411-67
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch73-116o1.2
Summary
Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome 11. Orthologous to human MRAS (muscle RAS oncogene homolog). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See mrasa in Genome Data Viewer
Location:
chromosome: 9
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (29040365..29060059)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (29229376..29249003)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase non-receptor type 4a Neighboring gene transmembrane protein 177 Neighboring gene parathyroid hormone 2 receptor a Neighboring gene uncharacterized LOC137496477 Neighboring gene 2-oxoglutarate receptor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GDP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ras-related protein M-Ras

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    29040365..29060059
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021478961.2 → XP_021334636.1  ras-related protein M-Ras

    UniProtKB/TrEMBL
    A0A8M9QG18, E7F5A7
    Related
    ENSDARP00000124094.1, ENSDART00000150201.2
    Conserved Domains (1) summary
    cl21455
    Location:12 → 176
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. XM_021478962.2 → XP_021334637.1  ras-related protein M-Ras

    UniProtKB/TrEMBL
    A0A8M9QG18, E7F5A7
    Conserved Domains (1) summary
    cl21455
    Location:12 → 176
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395284.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    310017..326741
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003199224.6 → XP_003199272.1  ras-related protein M-Ras

    See identical proteins and their annotated locations for XP_003199272.1

    UniProtKB/TrEMBL
    A0A8M9QG18, E7F5A7
    Conserved Domains (1) summary
    cl21455
    Location:12 → 176
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. XM_005167761.5 → XP_005167818.1  ras-related protein M-Ras

    See identical proteins and their annotated locations for XP_005167818.1

    UniProtKB/TrEMBL
    A0A8M9QG18, E7F5A7
    Conserved Domains (1) summary
    cl21455
    Location:12 → 176
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein
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